RabMAb

Anti-Caspase 5抗体[EP876Y] (ab40887)

概述

  • 产品名称Anti-Caspase 5抗体[EP876Y]
    参阅全部 Caspase 5 一抗
  • 描述
    兔单克隆抗体[EP876Y] to Caspase 5
  • 特异性Based on amino acids homology, this antibody will not recognize either p20 or p10 subunits of Caspase-5.
  • 经测试应用适用于: IHC-P, ICC/IF, IP, WBmore details
    不适用于: Flow Cyt
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to N-terminal residues of human Caspase-5

  • 阳性对照
    • HeLa cells, human breast carcinoma.
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

     

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
  • 纯度Tissue culture supernatant
  • 克隆单克隆
  • 克隆编号EP876Y
  • 同种型IgG
  • 研究领域

相关产品

应用

Our Abpromise guarantee covers the use of ab40887 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/50 - 1/100.
ICC/IF 1/100 - 1/250.
IP 1/50.
WB 1/1000 - 1/10000. Detects a band of approximately 47 kDa (predicted molecular weight: 47 kDa).
  • 应用说明Is unsuitable for Flow Cyt.
  • 靶标

    • 功能Mediator of programmed cell death (apoptosis).
    • 组织特异性Expressed in barely detectable amounts in most tissues except brain, highest levels being found in lung, liver and skeletal muscle.
    • 序列相似性Belongs to the peptidase C14A family.
      Contains 1 CARD domain.
    • 翻译后修饰The two subunits are derived from the precursor sequence by an autocatalytic mechanism.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Apoptosis related cysteine protease antibody
      • CASP-5 antibody
      • CASP5 antibody
      • CASP5_HUMAN antibody
      • Caspase-5 subunit p10 antibody
      • ICE(rel)-III antibody
      • ICERELIII antibody
      • ICH 3 antibody
      • ICH 3 protease antibody
      • Protease ICH-3 antibody
      • Protease TY antibody
      • TY antibody
      • TY protease antibody
      see all

    Anti-Caspase 5 antibody [EP876Y] 图像

    • Anti-Caspase 5 antibody [EP876Y] (ab40887) at 1/10000 dilution + HeLa cell lysate at 10 µg

      Predicted band size : 47 kDa
      Observed band size : 47 kDa
    • Stainign of Caspase 5 on paraffin-embedded human breast carcinoma sections, using ab40557 at a 1:50 dilution.
    • ab40887 staining HeLa cells for Caspase 5 (dilution 1:100).

    Anti-Caspase 5 antibody [EP876Y] (ab40887)参考文献

    This product has been referenced in:
    • Manchado E  et al. Targeting Mitotic Exit Leads to Tumor Regression In Vivo: Modulation by Cdk1, Mastl, and the PP2A/B55a,d Phosphatase. Cancer Cell 18:641-54 (2010). WB ; Mouse . Read more (PubMed: 21156286) »

    See 1 Publication for this product

    Product Wall

    Thank you for your enquiry. I have contacted the originators of these antibodies and here is the sequence information I obtained. ab25899: This immunogen sequence is proprietary, but we can run any alignments with the sequence that you require. ...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"