概述

  • 产品名称Anti-Caspase 5抗体
    参阅全部 Caspase 5 一抗
  • 描述
    兔多克隆抗体to Caspase 5
  • 特异性This antibody detects a cleaved fragment of activated CASP5 (the p10 subunit), resulting from cleavage adjacent to Ser331.
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthesized peptide derived from human CASP5.

  • 阳性对照
    • Extracts from 293 cells.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab69637 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately <19 kDa (predicted molecular weight: 10 kDa).
ELISA 1/20000.

靶标

  • 功能Mediator of programmed cell death (apoptosis).
  • 组织特异性Expressed in barely detectable amounts in most tissues except brain, highest levels being found in lung, liver and skeletal muscle.
  • 序列相似性Belongs to the peptidase C14A family.
    Contains 1 CARD domain.
  • 翻译后修饰The two subunits are derived from the precursor sequence by an autocatalytic mechanism.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Apoptosis related cysteine protease antibody
    • CASP-5 antibody
    • CASP5 antibody
    • CASP5_HUMAN antibody
    • Caspase-5 subunit p10 antibody
    • ICE(rel)-III antibody
    • ICERELIII antibody
    • ICH 3 antibody
    • ICH 3 protease antibody
    • Protease ICH-3 antibody
    • Protease TY antibody
    • TY antibody
    • TY protease antibody
    see all

Anti-Caspase 5 antibody 图像

  • All lanes : Anti-Caspase 5 antibody (ab69637) at 1/500 dilution

    Lane 1 : Extracts from 293 cells treated with etoposide (25uM, 1hour)
    Lane 2 : Extracts from 293 cells treated with etoposide (25uM, 1hour), with immunising cleavage peptide at 5 µg

    Lysates/proteins at 5 µg per lane.


    Predicted band size : 10 kDa
    Observed band size : <19 kDa (why is the actual band size different from the predicted?)

Anti-Caspase 5 antibody (ab69637)参考文献

ab69637 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab69637.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"