Anti-Caspase-2 (phospho S157)抗体(ab62441)

概述

  • 产品名称Anti-Caspase-2 (phospho S157)抗体
    参阅全部 Caspase-2 一抗
  • 描述
    兔多克隆抗体to Caspase-2 (phospho S157)
  • 特异性ab62441 detects endogenous levels of Caspase-2 only when phosphorylated at serine 157.
  • 经测试应用适用于: IHC-P, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse
  • 免疫原

    Synthetic peptide corresponding to Human Caspase-2.
    Database link: P42575

  • 阳性对照
    • Human lung carcinoma tissue.

性能

应用

Our Abpromise guarantee covers the use of ab62441 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/50 - 1/100.
ELISA 1/10000.

靶标

  • 功能Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.
  • 组织特异性Expressed at higher levels in the embryonic lung, liver and kidney than in the heart and brain. In adults, higher level expression is seen in the placenta, lung, kidney, and pancreas than in the heart, brain, liver and skeletal muscle.
  • 序列相似性Belongs to the peptidase C14A family.
    Contains 1 CARD domain.
  • 翻译后修饰The mature protease can process its own propeptide, but not that of other caspases.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CASP 2 antibody
    • CASP-2 antibody
    • Casp2 antibody
    • CASP2_HUMAN antibody
    • Caspase 2 antibody
    • Caspase 2 apoptosis related cysteine peptidase antibody
    • Caspase-2 subunit p12 antibody
    • Caspase2 antibody
    • ICH 1 antibody
    • ICH 1 protease antibody
    • ICH 1L antibody
    • ICH1 antibody
    • ICH1 protease antibody
    • ICH1L antibody
    • NEDD-2 antibody
    • NEDD2 antibody
    • Neural precursor cell expressed developmentally down-regulated protein 2 antibody
    • PPP1R57 antibody
    • Protease ICH-1 antibody
    • Protein phosphatase 1 regulatory subunit 57 antibody
    see all

Anti-Caspase-2 (phospho S157) antibody 图像

  • Immunofluorescence analysis of Caspase-2 in human lung carcinoma tissue (paraffin section), using ab62441 (1:50); in the presence or absence of phosphopeptide.

Anti-Caspase-2 (phospho S157) antibody (ab62441)参考文献

ab62441 has not yet been referenced specifically in any publications.

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