概述

描述

  • 性质Synthetic
  • 氨基酸序列

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技术指标

Our Abpromise guarantee covers the use of ab72738 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-Caspase-14 antibody (ab45415)

  • 形式Liquid

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle.

    PBS pH7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide.

常规信息

  • 别名
    • Apoptosis related cysteine protease
    • CASP 14
    • CASP-14
    • CASP14
    • Caspase 14 apoptosis related cysteine protease
    • Caspase 14 precursor
    • Caspase-14 subunit p10
    • Caspase14
    • CASPE_HUMAN
    • MGC119078
    • MGC119079
    • MICE
    • Mini ICE
    see all
  • 功能Believed to be a non-apoptotic caspase which is involved in epidermal differentiation. Seems to play a role in keratinocyte differentiation and cornification. Probably regulates maturation of the epidermis by proteolytically processing filaggrin.
  • 组织特异性Expressed in keratinocytes of adult skin suprabasal layers (from spinous layers to the stratum granulosum and stratum corneum) (at protein level). Expressed in keratinocytes of hair shaft and sebaceous glands (at protein level). In psoriatic skin only expressed at very low levels.
  • 序列相似性Belongs to the peptidase C14A family.
  • 细胞定位Cytoplasm. Nucleus.
  • Information by UniProt

Caspase-14 peptide (ab72738)参考文献

ab72738 has not yet been referenced specifically in any publications.

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