Anti-Caspase-14抗体[70A1426] (ab11920)

概述

  • 产品名称Anti-Caspase-14抗体[70A1426]
    参阅全部 Caspase-14 一抗
  • 描述
    小鼠单克隆抗体[70A1426] to Caspase-14
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Synthetic peptide corresponding to Human Caspase-14.
    Database link: P31944

  • 阳性对照
    • Mouse spleen cell extract.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 0.02% Sodium azide
    Constituent: PBS
  • Concentration information loading...
  • 纯度Protein G purified
  • 纯化说明This antibody is affinity purified.
  • 克隆单克隆
  • 克隆编号70A1426
  • 同种型IgG1
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab11920 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 30 kDa (predicted molecular weight: 29.04 kDa).

靶标

  • 功能Believed to be a non-apoptotic caspase which is involved in epidermal differentiation. Seems to play a role in keratinocyte differentiation and cornification. Probably regulates maturation of the epidermis by proteolytically processing filaggrin.
  • 组织特异性Expressed in keratinocytes of adult skin suprabasal layers (from spinous layers to the stratum granulosum and stratum corneum) (at protein level). Expressed in keratinocytes of hair shaft and sebaceous glands (at protein level). In psoriatic skin only expressed at very low levels.
  • 序列相似性Belongs to the peptidase C14A family.
  • 细胞定位Cytoplasm. Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Apoptosis related cysteine protease antibody
    • CASP 14 antibody
    • CASP-14 antibody
    • CASP14 antibody
    • Caspase 14 apoptosis related cysteine protease antibody
    • Caspase 14 precursor antibody
    • Caspase-14 subunit p10 antibody
    • Caspase14 antibody
    • CASPE_HUMAN antibody
    • MGC119078 antibody
    • MGC119079 antibody
    • MICE antibody
    • Mini ICE antibody
    see all

Anti-Caspase-14 antibody [70A1426] 图像

Anti-Caspase-14 antibody [70A1426] (ab11920)参考文献

ab11920 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your enquiry. This antibody was raised against a peptide corresponding to amino acids 2-18 of caspase 14, which is right in the pro-domain or including it (depending where the caspase 14 is processed, the first putative cleavage site bein...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"