Anti-Caseine Kinase 1 alpha抗体(ab64939)

概述

  • 产品名称Anti-Caseine Kinase 1 alpha抗体
    参阅全部 Casein Kinase 1 alpha 一抗
  • 描述
    兔多克隆抗体to Caseine Kinase 1 alpha
  • 特异性ab64939 detects endogenous levels of total Caseine Kinase 1 alpha protein.
  • 经测试应用适用于: WB, ELISA, IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide (Human) from an internal sequence.

  • 阳性对照
    • Human lung carcinoma tissue, HeLa cells and HeLa cell extracts.

性能

应用

Our Abpromise guarantee covers the use of ab64939 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
IHC-P
ICC/IF
  • 应用说明ELISA: 1/20000.
    ICC/IF: 1/500 - 1/1000.
    IHC-P: 1/50 - 1/100.
    WB: 1/500 - 1/1000. Detects a band of approximately 39 kDa (predicted molecular weight: 39 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May play a role in segregating chromosomes during mitosis.
    • 序列相似性Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.
      Contains 1 protein kinase domain.
    • 细胞定位Cytoplasm. Cytoplasm > cytoskeleton > centrosome. Chromosome > centromere > kinetochore. Nucleus speckle. Localizes to the centrosome in interphase cells, and to kinetochore fibers during mitosis.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Casein kinase 1 alpha 1 antibody
      • Casein kinase I isoform alpha antibody
      • CK1 antibody
      • CK1A antibody
      • CKI alpha antibody
      • CKI-alpha antibody
      • CKIa antibody
      • Clock regulator kinase antibody
      • Csnk1a1 antibody
      • Down regulated in lung cancer antibody
      • HLCDGP1 antibody
      • KC1A_HUMAN antibody
      • PRO2975 antibody
      see all

    Anti-Caseine Kinase 1 alpha antibody 图像

    • This image shows human lung carcinoma tissue stained with ab64939 at 1/50 dilution; with and without the immunizing peptide.
    • This image shows HeLa cells stained with ab64939 at 1/500 dilution; with and without the immunising peptide.
    • All lanes : Anti-Caseine Kinase 1 alpha antibody (ab64939) at 1/500 dilution

      Lane 1 : extracts from HeLa cells (5-30µg total protein)
      Lane 2 : extracts from HeLa cells (5-30µg total protein) with 5-10µg of the immunising peptide.


      Predicted band size : 39 kDa
      Observed band size : 39 kDa

    Anti-Caseine Kinase 1 alpha antibody (ab64939)参考文献

    ab64939 has not yet been referenced specifically in any publications.

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