Anti-Casein Kinase 1 alpha抗体[AT2E2] (ab88079)

概述

  • 产品名称Anti-Casein Kinase 1 alpha抗体[AT2E2]
    参阅全部 Casein Kinase 1 alpha 一抗
  • 描述
    小鼠单克隆抗体[AT2E2] to Casein Kinase 1 alpha
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length human protein Casein Kinase 1 alpha purified from E. coli (NP_001883)

  • 阳性对照
    • HeLa and MCF7 cell lysates

性能

应用

Our Abpromise guarantee covers the use of ab88079 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/2000. Predicted molecular weight: 39 kDa.
ELISA Use at an assay dependent dilution.

靶标

  • 功能Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May play a role in segregating chromosomes during mitosis.
  • 序列相似性Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.
    Contains 1 protein kinase domain.
  • 细胞定位Cytoplasm. Cytoplasm > cytoskeleton > centrosome. Chromosome > centromere > kinetochore. Nucleus speckle. Localizes to the centrosome in interphase cells, and to kinetochore fibers during mitosis.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Casein kinase 1 alpha 1 antibody
    • Casein kinase I isoform alpha antibody
    • CK1 antibody
    • CK1A antibody
    • CKI alpha antibody
    • CKI-alpha antibody
    • CKIa antibody
    • Clock regulator kinase antibody
    • Csnk1a1 antibody
    • Down regulated in lung cancer antibody
    • HLCDGP1 antibody
    • KC1A_HUMAN antibody
    • PRO2975 antibody
    see all

Anti-Casein Kinase 1 alpha antibody [AT2E2] 图像

  • All lanes : Anti-Casein Kinase 1 alpha antibody [AT2E2] (ab88079) at 1/1000 dilution

    Lane 1 : HeLa cell lysate
    Lane 2 : MCF7 cell lysate

    Lysates/proteins at 40 µg per lane.

    Secondary
    HRP conjugated goat anti-mouse IgG
    Developed using the ECL technique

    Predicted band size : 39 kDa
    Observed band size : 39 kDa

Anti-Casein Kinase 1 alpha antibody [AT2E2] (ab88079)参考文献

ab88079 has not yet been referenced specifically in any publications.

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