Anti-Cardiac Troponin T抗体[7e7] (HRP) (ab24452)


  • 产品名称Anti-Cardiac Troponin T抗体[7e7] (HRP)
    参阅全部 Cardiac Troponin T 一抗
  • 描述
    小鼠单克隆抗体[7e7] to Cardiac Troponin T (HRP)
  • 偶联物HRP
  • 特异性No cross reactivity with skeletal forms of the protein or TnC. Hybridoma cell line producing ab14541 [7E7] was raised after hybridization of myeloma cell line sp2/0 with splenocytes of mice immunized with human tertiary Tn complex. Thus ab14541 [7E7] demonstrates slight cross-reaction with cTnI (about 5 % based on ELISA data).
  • 经测试应用适用于: Sandwich ELISA, ELISA, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length native protein (purified) (Human)



Our Abpromise guarantee covers the use of ab24452 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Sandwich ELISA Use at an assay dependent dilution. Can be paired for Sandwich ELISA with Mouse monoclonal [1C11] to Cardiac Troponin T (ab8295). Can be used as Detection antibody. It is possible to use the following pairs in sELISA: coating - conjugate ab105438 - ab24452 ab105439 - ab24452 ab105440 - ab24452 ab105441 - ab24452
ELISA Use at an assay dependent dilution. Can be paired for ELISA with Mouse monoclonal [1C11] to Cardiac Troponin T (ab8295).
WB Use at an assay dependent dilution. Predicted molecular weight: 35.4 kDa.


  • 功能Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
  • 组织特异性Heart. The fetal heart shows a greater expression in the atrium than in the ventricle, while the adult heart shows a greater expression in the ventricle than in the atrium. Isoform 6 predominates in normal adult heart. Isoforms 1, 7 and 8 are expressed in fetal heart. Isoform 7 is also expressed in failing adult heart.
  • 疾病相关Defects in TNNT2 are the cause of cardiomyopathy familial hypertrophic type 2 (CMH2) [MIM:115195]. Familial hypertrophic cardiomyopathy is a hereditary heart disorder characterized by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea, syncope, collapse, palpitations, and chest pain. They can be readily provoked by exercise. The disorder has inter- and intrafamilial variability ranging from benign to malignant forms with high risk of cardiac failure and sudden cardiac death.
    Defects in TNNT2 are the cause of cardiomyopathy dilated type 1D (CMD1D) [MIM:601494]. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.
    Defects in TNNT2 are the cause of cardiomyopathy familial restrictive type 3 (RCM3) [MIM:612422]. Restrictive cardiomyopathy is a heart disorder characterized by impaired filling of the ventricles with reduced diastolic volume, in the presence of normal or near normal wall thickness and systolic function.
  • 序列相似性Belongs to the troponin T family.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Cardiac muscle troponin T antibody
    • Cardiomyopathy dilated 1D (autosomal dominant) antibody
    • Cardiomyopathy hypertrophic 2 antibody
    • CMD1D antibody
    • CMH2 antibody
    • CMPD2 antibody
    • cTnT antibody
    • LVNC6 antibody
    • MGC3889 antibody
    • OTTHUMP00000033864 antibody
    • OTTHUMP00000033865 antibody
    • OTTHUMP00000033866 antibody
    • OTTHUMP00000033867 antibody
    • OTTHUMP00000033870 antibody
    • OTTHUMP00000218095 antibody
    • RCM3 antibody
    • TNNT 2 antibody
    • TNNT2 antibody
    • TNNT2_HUMAN antibody
    • TnTc antibody
    • Troponin T cardiac muscle antibody
    • Troponin T type 2 (cardiac) antibody
    • Troponin T type 2 cardiac antibody
    • Troponin T, cardiac muscle antibody
    • Troponin T2 cardiac antibody
    see all

Anti-Cardiac Troponin T antibody [7e7] (HRP) (ab24452)参考文献

ab24452 has not yet been referenced specifically in any publications.

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