概述

  • 产品名称Anti-CARD12抗体
    参阅全部 CARD12 一抗
  • 描述
    兔多克隆抗体to CARD12
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Recombinant fragment, corresponding to amino acids 764-1019 of Human CARD12 (BC031555)

  • 阳性对照
    • Human fetal brain lysate

性能

应用

Our Abpromise guarantee covers the use of ab99860 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 116 kDa.
IHC-P 1/100 - 1/500.

靶标

  • 功能Plays a role in the promotion of apoptosis.
  • 组织特异性Isoform 2 is expressed ubiquitously, although highly expressed in lung and spleen. Isoform 1 is highly expressed in lung, followed by leukocytes especially monocytes, lymph node, colon, brain, prostate, placenta, spleen, bone marrow and fetal liver. Isoform 4 is only detected in brain.
  • 序列相似性Contains 1 CARD domain.
    Contains 14 LRR (leucine-rich) repeats.
    Contains 1 NACHT domain.
  • 细胞定位Cytoplasm. Cytoplasmic filaments.
  • Information by UniProt
  • 数据库链接
  • 别名
    • and NACHT-containing protein antibody
    • CARD 12 antibody
    • CARD antibody
    • CARD LRR and NACHT containing protein 1 antibody
    • CARD LRR and NACHT containing protein antibody
    • CARD12 antibody
    • Caspase recruitment domain containing protein 12 antibody
    • Caspase recruitment domain family member 12 antibody
    • Caspase recruitment domain-containing protein 12 antibody
    • CLAN 1 antibody
    • CLAN A antibody
    • CLAN antibody
    • CLAN B antibody
    • CLAN C antibody
    • CLAN D antibody
    • Clan protein antibody
    • CLAN1 antibody
    • CLANA antibody
    • CLANB antibody
    • CLANC antibody
    • CLAND antibody
    • CLR 2.1 antibody
    • CLR2.1 antibody
    • ICE protease activating factor antibody
    • Ice protease-activating factor antibody
    • Ipaf antibody
    • LRR antibody
    • NLR family CARD domain containing 4 antibody
    • NLR family CARD domain-containing protein 4 antibody
    • NLRC 4 antibody
    • NLRC4 antibody
    • NLRC4_HUMAN antibody
    • NOD like receptor C4 antibody
    • Nucleotide binding oligomerization domain leucine rich repeat and CARD domain containing 4 antibody
    • UNQ6189/PRO20215 antibody
    see all

Anti-CARD12 antibody 图像

  • Anti-CARD12 antibody (ab99860) at 1/500 dilution + Human fetal brain lysate

    Predicted band size : 116 kDa
  • Immunohistochemical staining of formalin-fixed paraffin-embedded human fetal lung showing cytoplasmic staining with ab99860 at a dilution of 1/100.

Anti-CARD12 antibody (ab99860)参考文献

This product has been referenced in:
  • Ataide MA  et al. Malaria-induced NLRP12/NLRP3-dependent caspase-1 activation mediates inflammation and hypersensitivity to bacterial superinfection. PLoS Pathog 10:e1003885 (2014). Read more (PubMed: 24453977) »

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab99860.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"