Anti-Carcino Embryonic Antigen CEA抗体[Col-1], prediluted (ab17238)

概述

  • 产品名称Anti-Carcino Embryonic Antigen CEA抗体[Col-1], prediluted
    参阅全部 Carcino Embryonic Antigen CEA 一抗
  • 描述
    小鼠单克隆抗体[Col-1] to Carcino Embryonic Antigen CEA, prediluted
  • 特异性This antibody reacts with a highly glycosylated protein of MW 180 kD, synthesized during development in the fetal gut and several tumors. It does not react with normal colon antigen (NCA). It stains the cell surface and cytoplasm of malignant glands in colorectal adenocarcinomas.
  • 经测试应用适用于: IHC-P, IHC-Frmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    BALB/C mice were injected with extract of colon carcinoma cells.

  • 阳性对照
    • Colon carcinoma

性能

应用

Our Abpromise guarantee covers the use of ab17238 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
IHC-Fr
  • 应用说明IHC-P: Use at an assay dependent dilution.
    IHC-Fr: Use at an assay dependent dilution (acetone fixed sections).

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins.
    • 组织特异性Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon.
    • 序列相似性Belongs to the immunoglobulin superfamily. CEA family.
      Contains 7 Ig-like (immunoglobulin-like) domains.
    • 翻译后修饰Complex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate.
    • 细胞定位Cell membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Carcinoembryonic antigen antibody
      • Carcinoembryonic antigen-related cell adhesion molecule 5 antibody
      • CD66e antibody
      • CEA antibody
      • Ceacam5 antibody
      • CEAM5_HUMAN antibody
      • DKFZp781M2392 antibody
      • Meconium antigen 100 antibody
      • OTTHUMP00000199032 antibody
      • OTTHUMP00000199033 antibody
      • OTTHUMP00000199034 antibody
      see all

    Anti-Carcino Embryonic Antigen CEA antibody [Col-1], prediluted 图像

    • ab17238 staining Carcino Embryonic Antigen CEA in human colon carcinoma tissue section by Immunohistochemistry (Formalin/ PFA fixed paraffin embedded tissue sections).

    Anti-Carcino Embryonic Antigen CEA antibody [Col-1], prediluted (ab17238)参考文献

    ab17238 has not yet been referenced specifically in any publications.

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