Anti-Carcino Embryonic Antigen CEA抗体(ab33562)

概述

  • 产品名称Anti-Carcino Embryonic Antigen CEA抗体
    参阅全部 Carcino Embryonic Antigen CEA 一抗
  • 描述
    兔多克隆抗体to Carcino Embryonic Antigen CEA
  • 特异性Recognizes human CEA and CEA like proteins such as non specific crossreacting antigen (NCA), NCA2, and biliary glycoprotein (BGP1). Has been absorbed with plasma proteins and blood group antigens A and B.
  • 经测试应用适用于: IP, WB, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
    不与反应: Dog
  • 免疫原

    Human Carcino Embryonic Antigen CEA isolated from hepatic metastasis of colon adenocarcinoma

  • 阳性对照
    • LS174T cells or colon carcinoma.

性能

应用

Our Abpromise guarantee covers the use of ab33562 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IP Use at an assay dependent concentration.
WB 1/200. Predicted molecular weight: 77 kDa.
IHC-P 1/500 - 1/1000. Antigen retrieval is not essential but may optimise staining.

靶标

  • 功能Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins.
  • 组织特异性Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon.
  • 序列相似性Belongs to the immunoglobulin superfamily. CEA family.
    Contains 7 Ig-like (immunoglobulin-like) domains.
  • 翻译后修饰Complex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate.
  • 细胞定位Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Carcinoembryonic antigen antibody
    • Carcinoembryonic antigen-related cell adhesion molecule 5 antibody
    • CD66e antibody
    • CEA antibody
    • Ceacam5 antibody
    • CEAM5_HUMAN antibody
    • DKFZp781M2392 antibody
    • Meconium antigen 100 antibody
    • OTTHUMP00000199032 antibody
    • OTTHUMP00000199033 antibody
    • OTTHUMP00000199034 antibody
    see all

Anti-Carcino Embryonic Antigen CEA antibody (ab33562)参考文献

This product has been referenced in:
  • Graham SA  et al. Identification of Neutrophil Granule Glycoproteins as Lewisx-containing Ligands Cleared by the Scavenger Receptor C-type Lectin. J Biol Chem 286:24336-49 (2011). WB ; Human . Read more (PubMed: 21561871) »

See 1 Publication for this product

Product Wall

Abcam has not validated the combination of species/application used in this Abreview.
Application Immunohistochemistry (Frozen sections)
Sample Rat Tissue sections (liver)
Specification liver
Fixative Acetone
Permeabilization No
Username

Dr. Krause

Verified customer

提交于 Feb 08 2010

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"