Anti-Carboxymethyl Lysine抗体[CMS-10] (ab30922)
Key features and details
- Mouse monoclonal [CMS-10] to Carboxymethyl Lysine
- Suitable for: ELISA, IHC-Fr, IHC-P
- Reacts with: Species independent
- Isotype: IgG1
概述
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产品名称
Anti-Carboxymethyl Lysine抗体[CMS-10]
参阅全部 Carboxymethyl Lysine 一抗 -
描述
小鼠单克隆抗体[CMS-10] to Carboxymethyl Lysine -
宿主
Mouse -
经测试应用
适用于: ELISA, IHC-Fr, IHC-Pmore details -
种属反应性
与反应: Species independent -
免疫原
N epsilon (Carboxymethyl) Lysine (CML) conjugated to KLH.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
Preservative: 0.1% Proclin 150
Ascites in stabilized buffer, containing 50% Block Ace (Casein-containing solution) and 0.1% ProClin as a preservative. -
Concentration information loading...
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纯度
Protein G purified -
克隆
单克隆 -
克隆编号
CMS-10 -
同种型
IgG1 -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab30922于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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ELISA |
Use a concentration of 0.1 - 0.5 µg/ml.
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IHC-Fr |
Use a concentration of 2 µg/ml.
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IHC-P | (1) |
Use at an assay dependent concentration.
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说明 |
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ELISA
Use a concentration of 0.1 - 0.5 µg/ml. |
IHC-Fr
Use a concentration of 2 µg/ml. |
IHC-P
Use at an assay dependent concentration. |
靶标
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相关性
N epsilon carboxymethyl lysine (CML or Carboxymethyl Lysine) is formed by the non enzymatic Schiff base reaction of glucose with proteins, followed by an Amadori rearrangement and oxidation that leaves only a carboxymethyl group attached to the lysine. The levels of CML adducts accumulate over time and have been used as an indicator of both serum glucose levels and oxidative protein damage. Elevated serum CML modified proteins have been associated with diabetes and may contribute to diabetic retinopathy, nephropathy and angiopathy. -
别名
- CML antibody
- N Epsilon (Carboxymethyl) Lysine antibody
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab30922 被引用在 2 文献中.
- Portal-Núñez S et al. Adverse Effects of Diabetes Mellitus on the Skeleton of Aging Mice. J Gerontol A Biol Sci Med Sci 71:290-9 (2016). PubMed: 26386012
- de la Maza MP et al. Weight increase is associated with skeletal muscle immunostaining for advanced glycation end products, receptor for advanced glycation end products, and oxidation injury. Rejuvenation Res 11:1041-8 (2008). IHC-P . PubMed: 19086911