Anti-Carbonic Anhydrase II抗体(HRP) (ab34586)

概述

  • 产品名称
    Anti-Carbonic Anhydrase II抗体(HRP)
    参阅全部 Carbonic Anhydrase II 一抗
  • 描述
    兔多克隆抗体to Carbonic Anhydrase II (HRP)
  • 偶联物
    HRP
  • 经测试应用
    适用于: WB, ELISA, Dot blotmore details
  • 种属反应性
    与反应: Cow
  • 免疫原

    Carbonic Anhydrase II (Bovine erythrocytes)

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at +4°C.
  • 存储溶液
    pH: 7.20
    Preservative: 0.01% Gentamicin sulphate
    Constituents: 1% BSA, 0.42% Potassium phosphate, 0.87% Sodium chloride
  • Concentration information loading...
  • 纯度
    IgG fraction
  • 纯化说明
    Purified by delipidation, salt fractionation and ion exchange chromatography.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab34586 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent concentration. Predicted molecular weight: 29 kDa.
ELISA Use at an assay dependent concentration.
Dot blot Use at an assay dependent concentration.

靶标

  • 功能
    Essential for bone resorption and osteoclast differentiation (By similarity). Reversible hydration of carbon dioxide. Can hydrates cyanamide to urea. Involved in the regulation of fluid secretion into the anterior chamber of the eye.
  • 疾病相关
    Defects in CA2 are the cause of osteopetrosis autosomal recessive type 3 (OPTB3) [MIM:259730]; also known as osteopetrosis with renal tubular acidosis, carbonic anhydrase II deficiency syndrome, Guibaud-Vainsel syndrome or marble brain disease. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. The disorder occurs in two forms: a severe autosomal recessive form occurring in utero, infancy, or childhood, and a benign autosomal dominant form occurring in adolescence or adulthood. Autosomal recessive osteopetrosis is usually associated with normal or elevated amount of non-functional osteoclasts. OPTB3 is associated with renal tubular acidosis, cerebral calcification (marble brain disease) and in some cases with mental retardation.
  • 序列相似性
    Belongs to the alpha-carbonic anhydrase family.
  • 细胞定位
    Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CA 2 antibody
    • CA II antibody
    • CA-II antibody
    • Ca2 antibody
    • CAC antibody
    • CAH2_HUMAN antibody
    • CAII antibody
    • Car 2 antibody
    • Car2 antibody
    • Carbonate dehydratase II antibody
    • Carbonic anhydrase 2 antibody
    • Carbonic anhydrase B antibody
    • Carbonic anhydrase C antibody
    • Carbonic anhydrase C, formerly antibody
    • Carbonic anhydrase II antibody
    • Carbonic dehydratase antibody
    • epididymis luminal protein 76 antibody
    • Epididymis secretory protein Li 282 antibody
    • HEL-76 antibody
    • HEL-S-282 antibody
    see all

实验方案

Anti-Carbonic Anhydrase II antibody (HRP) (ab34586)参考文献

ab34586 has not yet been referenced specifically in any publications.

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