Anti-CAMLG/CAML抗体(ab67714)
Key features and details
- Mouse polyclonal to CAMLG/CAML
- Suitable for: WB
- Reacts with: Rat, Human
- Isotype: IgG
概述
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产品名称
Anti-CAMLG/CAML抗体
参阅全部 CAMLG/CAML 一抗 -
描述
小鼠多克隆抗体to CAMLG/CAML -
宿主
Mouse -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Rat, Human -
免疫原
Recombinant full length protein within Human CAMLG/CAML aa 1-300. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.40
Constituent: 100% PBS -
Concentration information loading...
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纯度
Protein G purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab67714于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/500 - 1/1000. Predicted molecular weight: 33 kDa.
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说明 |
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WB
1/500 - 1/1000. Predicted molecular weight: 33 kDa. |
靶标
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相关性
The immunosuppressant drug cyclosporin A blocks a calcium dependent signal from the T cell receptor (TCR) that normally leads to T cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin. [Entrez Gene] -
细胞定位
Membrane; Multi pass membrane protein. -
数据库链接
- Entrez Gene: 819 Human
- Entrez Gene: 81715 Rat
- Omim: 601118 Human
- SwissProt: P49069 Human
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别名
- calcium modulating cyclophilin ligand antibody
- calcium modulating ligand antibody
- Calcium signal modulating cyclophilin ligand antibody
see all
图片
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Anti-CAMLG/CAML antibody (ab67714) at 1/500 dilution + rat brain at 25 µg
Secondary
Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution
Predicted band size: 33 kDa
Observed band size: 33 kDa -
All lanes : Anti-CAMLG/CAML antibody (ab67714) at 1/500 dilution
Lane 1 : CAMLG/CAML transfected 293T cell lysate
Lane 2 : non transfected 293T cell lysate
Lysates/proteins at 25 µg per lane.
Secondary
All lanes : Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution
Predicted band size: 33 kDa
Observed band size: 33 kDa
数据表及文件
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Datasheet download
文献 (1)
ab67714 被引用在 1 文献中.
- He B et al. The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88. Nat Immunol 11:836-45 (2010). WB, ICC/IF ; Human . PubMed: 20676093