Anti-CAMKIV抗体, prediluted (ab27490)

概述

  • 产品名称Anti-CAMKIV抗体, prediluted
    参阅全部 CAMKIV 一抗
  • 描述
    兔多克隆抗体to CAMKIV, prediluted
  • 特异性ab27490 recognises CAMKIV.
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human, Cynomolgus Monkey
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide:

    SAVGFEVPQQDVILPEY

    , corresponding to amino acids 457/473 of Human CAMKIV

  • 阳性对照
    • Human brain, Jurkat cells.

性能

应用

Our Abpromise guarantee covers the use of ab27490 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明IHC-P: use neat for 10 min at room temperature. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. In particular, boil tissue sections in 10mM citrate buffer pH 6.0 for 10 min and then cool at room temperature for 20 min.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. May be involved in transcriptional regulation. May be involved in regulation of microtubule dynamics. In vitro, phosphorylates CREB1, CREBBP, PRM2, MEF2A, MEF2D and STMN1/OP18. May be involved in spermatogenesis. May play a role in the consolidation/retention of hippocampus-dependent long-term memory.
    • 组织特异性Expressed in epithelial ovarian cancer tissue.
    • 序列相似性Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
      Contains 1 protein kinase domain.
    • 翻译后修饰Autophosphorylated and phosphorylated by CAMKK1 and CAMKK2 (By similarity). Dephosphorylated by serine/threonine protein phosphatase 2A, probably on Thr-200.
    • 细胞定位Cytoplasm. Nucleus. Substantial localization in certain neuronal nuclei. In spermatids associated with chromatin and nuclear matrix.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Brain Ca(2+) calmodulin dependent protein kinase type 4 antibody
      • Brain Ca(2+) calmodulin dependent protein kinase type IV antibody
      • Brain Ca++-calmodulin dependent protein kinase type IV antibody
      • Calcium / calmodulin dependent protein kinase type 4 catalytic chain antibody
      • Calcium / calmodulin dependent protein kinase type IV catalytic chain antibody
      • Calcium/calmodulin dependent protein kinase IV antibody
      • Calcium/calmodulin dependent protein kinase type IV antibody
      • Calcium/calmodulin-dependent protein kinase type IV antibody
      • CAM kinase 4 antibody
      • CAM kinase GR antibody
      • CAM kinase IV antibody
      • CAM kinase-GR antibody
      • CaMK 4 antibody
      • CAMK GR antibody
      • CaMK IV antibody
      • Camk4 antibody
      • CaMKGR antibody
      • IV antibody
      • KCC4_HUMAN antibody
      • MGC36771 antibody
      see all

    Anti-CAMKIV antibody, prediluted 图像

    • paraffin embedded formalin fixed human brain tissue section stained with anti CAMKIV (ab27490).

    Anti-CAMKIV antibody, prediluted (ab27490)参考文献

    ab27490 has not yet been referenced specifically in any publications.

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