Anti-CaMKII beta抗体(ab71709)

概述

  • 产品名称Anti-CaMKII beta抗体
    参阅全部 CaMKII beta 一抗
  • 描述
    兔多克隆抗体to CaMKII beta
  • 特异性This antibody does cross-react with CAMKII alpha protein
  • 经测试应用适用于: ELISA, IHC-P, WBmore details
  • 种属反应性
    与反应: Human, Monkey
  • 免疫原

    Synthetic peptide from the C-terminal region of human CaMKII beta conjugated to KLH

  • 阳性对照
    • Jurkat cell and primate lung tissue lysates. Human breast carcinoma tissue.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab71709 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/1000.
IHC-P 1/50 - 1/100.
WB 1/100 - 1/500. Detects a band of approximately 73 kDa (predicted molecular weight: 73 kDa).

靶标

  • 功能CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses, it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity.
  • 组织特异性Widely expressed. Expressed in adult and fetal brain. Expression is slightly lower in fetal brain.
  • 序列相似性Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
    Contains 1 protein kinase domain.
  • Information by UniProt
  • 数据库链接
  • 形式The multifunctional CaMKII beta, or Ca2+/calmodulin-dependent protein kinase II, is a well known effector of calcium- and calmodulin- mediated functions. It is present in many tissues but is most abundant in the brain. CaMKII is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits.
  • 别名
    • Calcium/calmodulin dependent protein kinase (CaM kinase) II beta antibody
    • Calcium/calmodulin dependent protein kinase II beta antibody
    • Calcium/calmodulin dependent protein kinase IIB antibody
    • Calcium/calmodulin dependent protein kinase type II beta chain antibody
    • calcium/calmodulin-dependent protein kinase II beta antibody
    • Calcium/calmodulin-dependent protein kinase type II subunit beta antibody
    • CAM 2 antibody
    • CaM kinase II beta chain antibody
    • CaM kinase II beta subunit antibody
    • CaM kinase II subunit beta antibody
    • CaM-kinase II beta chain antibody
    • CAM2 antibody
    • CAMK 2 antibody
    • CAMK 2B antibody
    • CaMK II beta subunit antibody
    • CaMK II subunit beta antibody
    • CaMK-II subunit beta antibody
    • CAMK2 antibody
    • CaMK2 beta antibody
    • Camk2b antibody
    • CAMKB antibody
    • CaMKII beta subunit antibody
    • CaMKIIB antibody
    • KCC2B_HUMAN antibody
    • MGC29528 antibody
    • Proline rich calmodulin dependent protein kinase antibody
    • proline rich calmodulin-dependent protein kinase antibody
    see all

Anti-CaMKII beta antibody 图像

  • All lanes : Anti-CaMKII beta antibody (ab71709) at 1/100 dilution

    Lane 1 : Jurkat cell lysate
    Lane 2 : primate lung tissue lysate

    Lysates/proteins at 12.5 µg per lane.


    Predicted band size : 73 kDa
    Observed band size : 73 kDa
  • ab71709 at 1/50 dilution, staining CaMKII beta in human breast carcinoma by Immunohistochemistry using formalin-fixed, paraffin-embedded tissue, followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-CaMKII beta antibody (ab71709)参考文献

ab71709 has not yet been referenced specifically in any publications.

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