功能Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. May regulate calcium-mediated granulocyte function. May play a role in apoptosis of erythroleukemia cells. Activates MAP kinase MAPK3 (By similarity). In vitro, phosphorylates transcription factor CREM isoform Beta and probably CREB1.
组织特异性Broadly expressed. Highly and mostly expressed in polymorphonuclear leukocytes (neutrophilic and eosinophilic granulocytes) while little or no expression is observed in monocytes and lymphocytes.
序列相似性Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily. Contains 1 protein kinase domain.
结构域The autoinhibitory domain overlaps with the calmodulin binding region and interacts in the inactive folded state with the catalytic domain as a pseudosubstrate.
细胞定位Cytoplasm. Nucleus. Predominantly cytoplasmic (Probable). Also nuclear upon activation.
Calcium/calmodulin dependent protein kinase ID antibody
Calcium/calmodulin dependent protein kinase type 1D antibody
Calcium/calmodulin-dependent protein kinase I-delta antibody
Calcium/calmodulin-dependent protein kinase type 1D antibody
CaM K1 antibody
CaM KI delta antibody
CaM kinase I delta antibody
CaM kinase ID antibody
CaM-KI delta antibody
CAMK 1D antibody
CaMKI delta antibody
CamKI like protein kinase antibody
CamKI-like protein kinase antibody
RP11 462F15.1 antibody
Anti-CAMK1D antibody 图像
Western blot - CAMK1D antibody (ab95178)
All lanes : Anti-CAMK1D antibody (ab95178) at 0.1 µg/ml
Lane 1 : HeLa whole cell lysate at 50 µg Lane 2 : HeLa whole cell lysate at 15 µg Lane 3 : HeLa whole cell lysate at 5 µg Lane 4 : 293T whole cell lysate at 50 µg
Developed using the ECL technique
Predicted band size : 43 kDa
Exposure time : 30 seconds
Immunoprecipitation - CAMK1D antibody (ab95178)
Lane 1: 3µg/ml ab95178 were used to immunoprecipitate CAMKD1 from 1mg HeLa whole cell lysate. 20% IP was loaded and probed with 1µg/ml ab95178.
Lane 2: same, using a control IgG. Detection: chemiluminescence with exposure time of 30 seconds.
Anti-CAMK1D antibody (ab95178)参考文献
has not yet been referenced specifically in any publications.