概述

  • 产品名称Anti-CAMK1D抗体
    参阅全部 CAMK1D 一抗
  • 描述
    兔多克隆抗体to CAMK1D
  • 经测试应用适用于: WB, IPmore details
  • 种属反应性
    与反应: Human
    预测可用于: Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • 免疫原

    Immunogen corresponds to a region between residue 335 and 385 (VSSSLSLASQ KDCLAPSTLC SFISSSSGVS GVGAERRPRP TTVTAVHSGS K), of Human CAMKD1 (NP_705718.1)

  • 阳性对照
    • HeLa and 293T whole cell lysates

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab95178 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/2000 - 1/10000. Predicted molecular weight: 43 kDa.
IP Use at 2-5 µg/mg of lysate.

靶标

  • 功能Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. May regulate calcium-mediated granulocyte function. May play a role in apoptosis of erythroleukemia cells. Activates MAP kinase MAPK3 (By similarity). In vitro, phosphorylates transcription factor CREM isoform Beta and probably CREB1.
  • 组织特异性Broadly expressed. Highly and mostly expressed in polymorphonuclear leukocytes (neutrophilic and eosinophilic granulocytes) while little or no expression is observed in monocytes and lymphocytes.
  • 序列相似性Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
    Contains 1 protein kinase domain.
  • 结构域The autoinhibitory domain overlaps with the calmodulin binding region and interacts in the inactive folded state with the catalytic domain as a pseudosubstrate.
  • 细胞定位Cytoplasm. Nucleus. Predominantly cytoplasmic (Probable). Also nuclear upon activation.
  • Information by UniProt
  • 数据库链接
  • 别名
    • A630059D12Rik antibody
    • Calcium/calmodulin dependent protein kinase ID antibody
    • Calcium/calmodulin dependent protein kinase type 1D antibody
    • Calcium/calmodulin-dependent protein kinase I-delta antibody
    • Calcium/calmodulin-dependent protein kinase type 1D antibody
    • CaM K1 antibody
    • CaM KI delta antibody
    • CaM kinase I delta antibody
    • CaM kinase ID antibody
    • CaM-KI delta antibody
    • CAMK 1D antibody
    • CAMK1D antibody
    • CaMKI delta antibody
    • CamKI like protein kinase antibody
    • CamKI-like protein kinase antibody
    • CaMKID antibody
    • CKLiK antibody
    • E030025C11Rik antibody
    • KCC1D_HUMAN antibody
    • OTTHUMP00000019119 antibody
    • OTTHUMP00000019120 antibody
    • OTTHUMP00000045030 antibody
    • RP11 462F15.1 antibody
    see all

Anti-CAMK1D antibody 图像

  • All lanes : Anti-CAMK1D antibody (ab95178) at 0.1 µg/ml

    Lane 1 : HeLa whole cell lysate at 50 µg
    Lane 2 : HeLa whole cell lysate at 15 µg
    Lane 3 : HeLa whole cell lysate at 5 µg
    Lane 4 : 293T whole cell lysate at 50 µg

    Developed using the ECL technique

    Predicted band size : 43 kDa


    Exposure time : 30 seconds
  • Lane 1: 3µg/ml ab95178 were used to immunoprecipitate CAMKD1 from 1mg HeLa whole cell lysate. 20% IP was loaded and probed with 1µg/ml ab95178.
    Lane 2: same, using a control IgG.
    Detection: chemiluminescence with exposure time of 30 seconds.

Anti-CAMK1D antibody (ab95178)参考文献

ab95178 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab95178.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"