Anti-Calsequestrin抗体(ab15611)

概述

  • 产品名称
    Anti-Calsequestrin抗体
    参阅全部 Calsequestrin 一抗
  • 描述
    兔多克隆抗体to Calsequestrin
  • 特异性
    Recognizes cardiac Calsequestrin very strongly, but also recognizes skeletal Calsequestrin.
  • 经测试应用
    适用于: WB, ICCmore details
  • 种属反应性
    与反应: Rat, Dog
    预测可用于: Human
  • 免疫原

    Full length native protein (purified) corresponding to Dog Calsequestrin.

性能

应用

Our Abpromise guarantee covers the use of ab15611 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 60 kDa.

Calsequestrin always forms high molecular weight aggregates which are unavoidable so they always show up on the top of the gel. This is common for all known anti-CSQ antibodies and has been described in many papers in the past.

ICC Use at an assay dependent concentration.

靶标

  • 功能
    Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle. The release of calcium bound to calsequestrin through a calcium release channel triggers muscle contraction. Binds 40 to 50 moles of calcium. Also binds laminin.
  • 序列相似性
    Belongs to the calsequestrin family.
  • 细胞定位
    Sarcoplasmic reticulum lumen. Mitochondrion. This isoform of calsequestrin occurs in the sarcoplasmic reticulum's terminal cisternae luminal spaces of fast skeletal muscle cells. Also mitochondrial according to PubMed:7945294.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Calmitin antibody
    • Calsequestrin 1 antibody
    • Calsequestrin 1 fast twitch skeletal muscle antibody
    • Calsequestrin 2 antibody
    • Calsequestrin 2 fast twitch cardiac muscle antibody
    • Calsequestrin antibody
    • Calsequestrin cardiac muscle isoform antibody
    • Calsequestrin skeletal muscle isoform antibody
    • Calsequestrin-1 antibody
    • Cardiac calsequestrin 2 antibody
    • CASQ 1 antibody
    • CASQ 2 antibody
    • Casq1 antibody
    • CASQ1_HUMAN antibody
    • PDIB1 antibody
    • PDIB2 antibody
    • Skeletal muscle calsequestrin 1 antibody
    • skeletal muscle isoform antibody
    see all

图片

  • Anti-Calsequestrin antibody (ab15611) at 1/500 dilution + purified dog cardiac calsequestrin

    Western blot using ab15611 at 1/500 on purified dog cardiac calsequestrin.

    Calsequestrin always forms high molecular weight aggregates which are unavoidable so they always show up on the top of the gel. This is common for all known anti-CSQ antibodies and has been described in many papers in the past.

    Calsequestrin always forms high molecular weight aggregates which are unavoidable so they always show up on the top of the gel. This is common for all known anti-CSQ antibodies and has been described in many papers in the past.

文献

ab15611 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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