Anti-Calsequestrin 2抗体(ab54858)

概述

  • 产品名称Anti-Calsequestrin 2抗体
    参阅全部 Calsequestrin 2 一抗
  • 描述
    小鼠单克隆抗体to Calsequestrin 2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Recombinant Fragment
    预测可用于: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 20-400 of Human Calsequestrin 2

性能

应用

Our Abpromise guarantee covers the use of ab54858 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle. The release of calcium bound to calsequestrin through a calcium release channel triggers muscle contraction. Binds 40 to 50 moles of calcium.
    • 疾病相关Defects in CASQ2 are the cause of catecholaminergic polymorphic ventricular tachycardia type 2 (CPVT2) [MIM:611938]; also known as stress-induced polymorphic ventricular tachycardia (VTSIP). CPVT2 is an autosomal recessive form of arrhythmogenic disorder characterized by stress-induced, bidirectional ventricular tachycardia that may degenerate into cardiac arrest and cause sudden death.
    • 序列相似性Belongs to the calsequestrin family.
    • 细胞定位Sarcoplasmic reticulum lumen. This isoform of calsequestrin occurs in the sarcoplasmic reticulum's terminal cisternae luminal spaces of cardiac and slow skeletal muscle cells.
    • Information by UniProt
    • 数据库链接
    • 别名
      • AA033488 antibody
      • AW146219 antibody
      • Calsequestrin 2 (cardiac muscle) antibody
      • Calsequestrin 2 fast twitch cardiac muscle antibody
      • Calsequestrin antibody
      • Calsequestrin cardiac muscle isoform antibody
      • Calsequestrin fast twitch cardiac muscle antibody
      • Calsequestrin-2 antibody
      • Calsequestrin2 antibody
      • cardCSQ antibody
      • Cardiac calsequestrin 2 antibody
      • cardiac muscle isoform antibody
      • CASQ 2 antibody
      • CASQ2 antibody
      • CASQ2_HUMAN antibody
      • cCSQ antibody
      • ESTM52 antibody
      • FLJ26321 antibody
      • FLJ93514 antibody
      • PDIB2 antibody
      see all

    Anti-Calsequestrin 2 antibody 图像

    • Western blot against tagged recombinant protein immunogen using ab54858 Calsequestrin 2 antibody at 1ug/ml. Predicted band size of immunogen is 68 kDa.

      This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Anti-Calsequestrin 2 antibody (ab54858)参考文献

    ab54858 has not yet been referenced specifically in any publications.

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