概述

  • 产品名称Anti-Calpain 1抗体
    参阅全部 Calpain 1 一抗
  • 描述
    小鼠多克隆抗体to Calpain 1
  • 经测试应用适用于: WB, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length Human Calpain 1 (NP_005177.2)

  • 阳性对照
    • Calpain 1 transfected 293T cell lysate, Human liver tissue lysate, HeLa cells.

性能

应用

Our Abpromise guarantee covers the use of ab89778 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 82 kDa.
ICC/IF Use a concentration of 10 µg/ml.

靶标

  • 功能Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.
  • 组织特异性Ubiquitous.
  • 序列相似性Belongs to the peptidase C2 family.
    Contains 1 calpain catalytic domain.
    Contains 4 EF-hand domains.
  • 细胞定位Cytoplasm. Cell membrane. Translocates to the plasma membrane upon Ca(2+) binding.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Ca2 activated neutral protease antibody
    • Calcium activated neutral proteinase antibody
    • Calcium activated neutral proteinase small subunit antibody
    • Calcium dependent protease small subunit 1 antibody
    • Calcium dependent protease small subunit antibody
    • Calcium-activated neutral proteinase 1 antibody
    • Calpain 1 antibody
    • Calpain 1 large subunit antibody
    • Calpain 1, (mu/I) large subunit antibody
    • Calpain mu type antibody
    • Calpain mu-type antibody
    • Calpain regulatory subunit antibody
    • Calpain small subunit 1 antibody
    • Calpain, large polypeptide L1 antibody
    • Calpain-1 catalytic subunit antibody
    • Calpain-1 large subunit antibody
    • CAN1_HUMAN antibody
    • CANP 1 antibody
    • CANP antibody
    • CANP small subunit antibody
    • CANP1 antibody
    • CANPL 1 antibody
    • CANPL1 antibody
    • CAPN 1 antibody
    • CAPN1 antibody
    • Cell proliferation inducing protein 30 antibody
    • Cell proliferation-inducing gene 30 protein antibody
    • Micromolar Calpain antibody
    • Micromolar-calpain antibody
    • Mu Calpain antibody
    • muCANP antibody
    • muCL antibody
    see all

Anti-Calpain 1 antibody 图像

  • Anti-Calpain 1 antibody (ab89778) at 1 µg/ml + human liver tissue lysate at 50 µg

    Predicted band size : 82 kDa
    Observed band size : 82 kDa
  • All lanes : Anti-Calpain 1 antibody (ab89778) at 1 µg/ml

    Lane 1 : Calpain 1 transfected 293T cell lysate
    Lane 2 : Non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 82 kDa
    Observed band size : 82 kDa
  • ab89778, at 10 ug/ml, staining Calpain 1 in HeLa cells by Immunofluorescence.

Anti-Calpain 1 antibody (ab89778)参考文献

This product has been referenced in:
  • Wanichawan P  et al. Molecular basis of calpain cleavage and inactivation of the sodium-calcium exchanger 1 in heart failure. J Biol Chem 289:33984-98 (2014). ICC ; Rat . Read more (PubMed: 25336645) »

See 1 Publication for this product

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