概述

  • 产品名称Anti-Calmodulin抗体[J4D8]
    参阅全部 Calmodulin 一抗
  • 描述
    小鼠单克隆抗体[J4D8] to Calmodulin
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant human Calmodulin (1-149aa) purified from E. coli

  • 阳性对照
    • NIH 3T3 cell lysate
  • 常规说明Myeloma cell line: mouse FO

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab75207 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 17 kDa (predicted molecular weight: 17 kDa).
ELISA Use at an assay dependent dilution.

靶标

  • 功能Calmodulin mediates the control of a large number of enzymes and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Together with CEP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis.
  • 序列相似性Belongs to the calmodulin family.
    Contains 4 EF-hand domains.
  • 翻译后修饰Ubiquitination results in a strongly decreased activity.
    Phosphorylation results in a decreased activity.
  • 细胞定位Cytoplasm > cytoskeleton > spindle. Cytoplasm > cytoskeleton > spindle pole. Distributed throughout the cell during interphase, but during mitosis becomes dramatically localized to the spindle poles and the spindle microtubules.
  • Information by UniProt
  • 数据库链接
  • 形式There are three genes which encode an identical calcium binding protein which is one of the four subunits of phosphorylase kinase.
  • 别名
    • CALM 1 antibody
    • CALM 2 antibody
    • CALM 3 antibody
    • CALM antibody
    • CALM_HUMAN antibody
    • CALM1 antibody
    • CALM2 antibody
    • Calm3 antibody
    • CALML2 antibody
    • calmodulin 1 (phosphorylase kinase, delta) antibody
    • Calmodulin 2 (phosphorylase kinase, delta) antibody
    • Calmodulin 3 (phosphorylase kinase, delta) antibody
    • Calmodulin antibody
    • CaM antibody
    • CAM I antibody
    • CAM1 antibody
    • CAM2 antibody
    • CAM3 antibody
    • CAMB antibody
    • CAMC antibody
    • CAMI antibody
    • CAMII antibody
    • CPVT4 antibody
    • DD132 antibody
    • FLJ99410 antibody
    • LP7057 protein antibody
    • PHKD antibody
    • PHKD2 antibody
    • PHKD3 antibody
    • phosphorylase kinase delta antibody
    • phosphorylase kinase, delta subunit antibody
    see all

Anti-Calmodulin antibody [J4D8] 图像

  • Anti-Calmodulin antibody [J4D8] (ab75207) at 1/500 dilution + NIH3T3 cell lysates at 50 µg

    Secondary
    goat anti-mouse HRP
    Developed using the ECL technique

    Predicted band size : 17 kDa
    Observed band size : 17 kDa

Anti-Calmodulin antibody [J4D8] (ab75207)参考文献

This product has been referenced in:
  • Dionisio N  et al. Functional role of the calmodulin- and inositol 1,4,5-trisphosphate receptor-binding (CIRB) site of TRPC6 in human platelet activation. Cell Signal 23:1850-6 (2011). WB, IP ; Human . Read more (PubMed: 21757000) »

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab75207.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"