概述

  • 产品名称Anti-CALHM1抗体
    参阅全部 CALHM1 一抗
  • 描述
    兔多克隆抗体to CALHM1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse
    预测可用于: Rat, Rabbit, Horse, Cow, Cat, Dog, Human, Pig
  • 免疫原

    Synthetic peptide corresponding to a region within C terminal amino acids 295-344 (GITDQGTMNR LLTSWHKCKP PLRLGQEAPL MSNGWAGGEP RPPRKEVATY) of Mouse CALHM1 (NP_001074740).

  • 阳性对照
    • Mouse Intestine lysate.

性能

应用

Our Abpromise guarantee covers the use of ab116101 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 39 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能May be a pore-forming ion channel. Controls cytosolic Ca(2+) permeability and cytosolic Ca(2+) concentration. Controls amyloid precursor protein (APP) proteolysis and aggregated amyloid-beta (Abeta) peptides levels in a Ca(2+) dependent manner.
  • 组织特异性Predominantly expressed in adult brain. Detected also in retinoic acid-differentiated SH-SY5Y cells.
  • 序列相似性Belongs to the FAM26 family.
  • 细胞定位Cell membrane. Endoplasmic reticulum membrane. Colocalizes with HSPA5 at the endoplasmic reticulum.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CAHM1_HUMAN antibody
    • Calcium homeostasis modulator 1 antibody
    • Calcium homeostasis modulator protein 1 antibody
    • CALHM1 antibody
    • FAM26C antibody
    • Family with sequence similarity 26, member C antibody
    • MGC39514 antibody
    • MGC39617 antibody
    • OTTHUMP00000020413 antibody
    • Protein FAM26C antibody
    see all

Anti-CALHM1 antibody 图像

  • Anti-CALHM1 antibody (ab116101) at 1 µg/ml + Mouse intestine lysate at 10 µg

    Predicted band size : 39 kDa

Anti-CALHM1 antibody (ab116101)参考文献

ab116101 has not yet been referenced specifically in any publications.

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