Anti-Calcitonin抗体, prediluted (ab8548)


  • 产品名称Anti-Calcitonin抗体, prediluted
    参阅全部 Calcitonin 一抗
  • 描述
    兔多克隆抗体to Calcitonin, prediluted
  • 特异性This antibody stains specifically for human parafollicular cells (C-cells) of normal and hyperplastic thyroid as well as medullary thyroid carcinoma. No staining of other cells or tissues has been observed.
  • 经测试应用适用于: WB, IHC-FoFr, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Sheep, Horse, Dog, Pig
  • 免疫原

    Synthetic human calcitonin 1-32.

  • 阳性对照
    • Medullary carcinoma of the thyroid or thyroid c-cell hyperplasia.
  • 常规说明This antibody has been quality controled using formalin-fixed paraffin-embedded human thyroid tissue sections.



Our Abpromise guarantee covers the use of ab8548 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent dilution. Predicted molecular weight: 15 kDa.
IHC-FoFr Use at an assay dependent dilution.
The prediluted antibody can be used on frozen cryostat sections as well as formalin-fixed paraffin-embedded tissue sections. For paraffin-embedded tissue sections, we recommend an incubation time and temperature of 30 minutes at 37°C for this antibody. N.B Prolonged fixation in buffered formalin can destroy the epitope.
IHC-P Use at an assay dependent dilution.


  • 相关性Calcitonin is a 32 amino acid peptide hormone synthesized by the parafollicular cells of the thyroid. It causes a rapid, but short lived, reduction in serum calcium and phosphate by promoting the incorporation of those ions in the bones. This effect is opposite to that of parathyroid hormone. Staining for calcitonin may be used for the identification of a spectrum of C cell proliferative abnormalities ranging from C cell hyperplasia to invasive tumors. Staining for calcitonin in medullary carcinoma of the thyroid produces a fine granular pattern in the cytoplasm. Amyloid deposits within the tumor may also exhibit varying degrees of calcitonin activity.
  • 细胞定位Cytoplasmic and Secreted
  • 数据库链接
  • 别名
    • Alpha CGRP antibody
    • alpha type CGRP antibody
    • CALC 1 antibody
    • CALC A antibody
    • CALC1 antibody
    • calcitonin 1 antibody
    • calcitonin gene related peptide 1 antibody
    • calcitonin gene related peptide I antibody
    • calcitonin related polypeptide alpha antibody
    • CGRP 1 antibody
    • CGRP antibody
    • CGRP I antibody
    • CGRP1 antibody
    • CT antibody
    • katacalcin antibody
    • KC antibody
    see all

Anti-Calcitonin antibody, prediluted 图像

  • Anti-Calcitonin antibody, prediluted (ab8548) at 1/25 dilution + Human thyroid lysate

    Predicted band size : 15 kDa
    Observed band size : 14 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 40 kDa. We are unsure as to the identity of these extra bands.

Anti-Calcitonin antibody, prediluted (ab8548)参考文献

ab8548 has not yet been referenced specifically in any publications.

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