Psychostimulant. Adenosine A1 and A2A receptor antagonist. Inhibits cAMP phosphodiesterases. Activates ryanodine receptor and induces intracellular calcium release.
Store at Room Temperature. The product can be stored for up to 12 months.
Soluble in water to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Antoniou K et al. A detailed behavioral analysis of the acute motor effects of caffeine in the rat: involvement of adenosine A1 and A2A receptors. Psychopharmacology (Berl)183:154-62 (2005).
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Nehlig A et al. Caffeine and the central nervous system: mechanisms of action, biochemical, metabolic and psychostimulant effects. Brain Res Brain Res Rev17:139-70 (0).
Read more (PubMed: 1356551) »