Anti-Cadherin like 23抗体(ab81981)

概述

  • 产品名称Anti-Cadherin like 23抗体
    参阅全部 Cadherin like 23 一抗
  • 描述
    山羊多克隆抗体to Cadherin like 23
  • 特异性ab81981 is expected to recognize both reported isoforms (NP_071407.3; NP_443068.1).
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide:

    C-YNISLYENVTVGTS

    , corresponding to internal sequence amino acids 465-478 of Human Cadherin like 23 (NP_071407.3; NP_443068.1)

  • 阳性对照
    • Human Brain (Amygdala and Frontal Cortex) lysates.

性能

应用

Our Abpromise guarantee covers the use of ab81981 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
  • 应用说明Peptide ELISA: Antibody detection limit dilution 1/1000.
    WB: Use at a concentration of 1 - 3 µg/ml. Detects a band of approximately 59 kDa (predicted molecular weight: 59 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性Cadherin like 23 (or Cadherin 23) is, like other members of the cadherin family, a calcium-dependent cell adhesion glycoprotein that preferentially interacts with itself in connecting cells. It is a single pass type I membrane protein that contains 27 cadherin domains. Cadherin like 23 is expressed in the neurosensory epithelium, where it is thought to be involved in stereocilia organisation and hair bundle formation. Defects in the gene encoding Cadherin like 23 are a cause of Usher syndrome, which is characterised by profound congenital sensorineural deafness and eventual blindness. Mutations in this gene are also a cause of non-syndromic sensorineural deafness autosomal recessive type 12 (DFNB12). Cadherin like 23 has also been associated with age-related hearing loss.
    • 细胞定位Cell membrane; Single-pass type I membrane protein
    • 数据库链接
    • 别名
      • Age related hearing loss 1 antibody
      • Ahl 1 antibody
      • Ahl antibody
      • Ahl1 antibody
      • Bob antibody
      • Bobby antibody
      • Bus antibody
      • Bustling antibody
      • Cadherin 23 antibody
      • Cadherin23 antibody
      • CDH 23 antibody
      • Mdfw antibody
      • Modifier of deaf waddler antibody
      • nmf112 antibody
      • nmf181 antibody
      • nmf252 antibody
      • Otocadherin antibody
      • USH 1D antibody
      • USH1 D antibody
      • USH1D antibody
      • Waltzer antibody
      see all

    Anti-Cadherin like 23 antibody 图像

    • Anti-Cadherin like 23 antibody (ab81981) at 1 µg/ml + Human Amygdala lysate (in RIPA buffer) at 35 µg
      Developed using the ECL technique

      Predicted band size : 59 kDa
      Observed band size : 59 kDa

    Anti-Cadherin like 23 antibody (ab81981)参考文献

    ab81981 has not yet been referenced specifically in any publications.

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