概述

  • 产品名称CAD肽

描述

  • 性质Synthetic

技术指标

Our Abpromise guarantee covers the use of ab8432 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking

    Western blot

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    PBS with 0.1% BSA 0.02% sodium azide pH7.2

常规信息

  • 别名
    • Aspartate carbamoyltransferase
    • Aspartate transcarbamylase
    • CAD protein
    • CAD trifunctional protein
    • Carbamoyl phosphate synthetase 2
    • CPSase ATCase DHOase
    • Dihydroorotase
    • Glutamine dependent carbamoyl phosphate synthase
    • Multifunctional protein CAD
    see all
  • 相关性Carbamoyl phosphate synthetase-aspartate carbamoyltransferase-dihydroorotase (CAD) is a multifunctional protein that initiates and regulates mammalian de novo pyrimidine biosynthesis. This trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis is the rate-limiting step in the de novo pyrimidine synthetic pathway. Although most of the CAD protein in the cell is cytosolic, phosphorylation at threonine 456 localizes the protein to the nucleus. While MAPK and EGF phosphorylate CAD at threonine 456, MAPK and c-myc have been found to induce over-expression of CAD.
  • 细胞定位Cytoplasmic and Nuclear

CAD peptide (ab8432)参考文献

ab8432 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"