概述

描述

  • 性质Synthetic
  • 氨基酸序列
    • 种属Human
    • 序列C-SPGGYSHDSRHRL
    • 氨基酸508 to 520

相关产品

技术指标

Our Abpromise guarantee covers the use of ab45660 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-CACNB4 antibody (ab26060)

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

常规信息

  • 别名
    • CAB4
    • CACB4_HUMAN
    • Cacnb4
    • CACNLB4
    • Calcium channel voltage dependent beta 4 subunit
    • Calcium channel voltage dependent subunit beta 4
    • Calcium channel voltage-dependent subunit beta 4
    • Dihydropyridine sensitive L type calcium channel beta 4 subunit
    • EA5
    • EIG9
    • EJM
    • EJM4
    • EJM6
    • Voltage-dependent L-type calcium channel subunit beta-4
    see all
  • 功能The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
  • 组织特异性Expressed predominantly in the cerebellum and kidney.
  • 疾病相关Genetic variations in CACNB4 are the cause of susceptibility to idiopathic generalized epilepsy type 9 (IGE9) [MIM:607682]. IGE9 is characterized by recurring generalized seizures in the absence of detectable brain lesions and/or metabolic abnormalities. Generalized seizures arise diffusely and simultaneously from both hemispheres of the brain.
    Genetic variations in CACNB4 are the cause of susceptibility to juvenile myoclonic epilepsy type 6 (EJM6) [MIM:607682]. EJM6 is a subtype of idiopathic generalized epilepsy. Patients have afebrile seizures only, with onset in adolescence (rather than in childhood) and myoclonic jerks which usually occur after awakening and are triggered by sleep deprivation and fatigue.
  • 序列相似性Belongs to the calcium channel beta subunit family.
    Contains 1 SH3 domain.
  • Information by UniProt

CACNB4 peptide (508-520) (ab45660)参考文献

ab45660 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab45660.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"