Anti-CAB3抗体(ab16717)
Key features and details
- Rabbit polyclonal to CAB3
- Suitable for: IP, ICC/IF, WB
- Reacts with: Rat
- Isotype: IgG
概述
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产品名称
Anti-CAB3抗体 -
描述
兔多克隆抗体to CAB3 -
宿主
Rabbit -
特异性
This antibody recognises the beta 3 calcium channel subunit. -
经测试应用
适用于: IP, ICC/IF, WBmore details -
种属反应性
与反应: Rat -
免疫原
Synthetic peptide corresponding to CAB3 aa 1-15 conjugated to keyhole limpet haemocyanin.
Sequence:MYDDSYVPGFEDSEA
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阳性对照
- Rat cortical and hippocampal, neuronal membranes. Negative control: non neuronal cells
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.40
Preservative: 0.08% Sodium azide
Constituent: PBS -
Concentration information loading...
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纯度
Ammonium Sulphate Precipitation -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab16717于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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IP |
Use at an assay dependent concentration.
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ICC/IF |
Use at an assay dependent concentration.
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WB | (1) |
Use at an assay dependent concentration.
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说明 |
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IP
Use at an assay dependent concentration. |
ICC/IF
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. |
靶标
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功能
The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. -
组织特异性
Expressed mostly in brain, smooth muscle and ovary. -
序列相似性
Belongs to the calcium channel beta subunit family.
Contains 1 SH3 domain. - Information by UniProt
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数据库链接
- Entrez Gene: 25297 Rat
- SwissProt: P54287 Rat
- Unigene: 2808 Rat
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别名
- CAB3 antibody
- CACB3_HUMAN antibody
- Cacnb3 antibody
see all
实验方案
数据表及文件
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Datasheet download
文献 (1)
ab16717 被引用在 1 文献中.
- Uriu Y et al. Rab3-interacting molecule gamma isoforms lacking the Rab3-binding domain induce long lasting currents but block neurotransmitter vesicle anchoring in voltage-dependent P/Q-type Ca2+ channels. J Biol Chem 285:21750-67 (2010). WB ; Human . PubMed: 20452978