概述

  • 产品名称Anti-CACNB3抗体
    参阅全部 CACNB3 一抗
  • 描述
    兔多克隆抗体to CACNB3
  • 特异性This antibody recognises the beta 3 calcium channel subunit.
  • 经测试应用适用于: WB, IP, ICC/IFmore details
  • 种属反应性
    与反应: Rat
  • 免疫原

    Synthetic peptide:

    MYDDSYVPGFEDSEA

    conjugated to KLH, corresponding to amino acids 1-15 of CACNB3.

  • 阳性对照
    • Rat cortical and hippocampal, neuronal membranes. Negative control: non neuronal cells

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 0.08% Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab16717 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000. Predicted molecular weight: 58 kDa.
IP Use at an assay dependent dilution.
ICC/IF Use at an assay dependent dilution.

靶标

  • 功能The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
  • 组织特异性Expressed mostly in brain, smooth muscle and ovary.
  • 序列相似性Belongs to the calcium channel beta subunit family.
    Contains 1 SH3 domain.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CAB3 antibody
    • CACB3_HUMAN antibody
    • Cacnb3 antibody
    • CACNLB3 antibody
    • Calcium channel voltage dependent beta 3 subunit antibody
    • Calcium channel voltage-dependent subunit beta 3 antibody
    • FLJ58949 antibody
    • Voltage-dependent L-type calcium channel subunit beta-3 antibody
    see all

Anti-CACNB3 antibody 图像



  • Predicted band size : 58 kDa

    Image from Uriu Y et al, J Biol Chem. 2010 Jul 9;285(28):21750-67. Epub 2010 May 7, Fig 7. DOI 10.1074/jbc.M110.101311

Anti-CACNB3 antibody (ab16717)参考文献

This product has been referenced in:
  • Uriu Y  et al. Rab3-interacting molecule gamma isoforms lacking the Rab3-binding domain induce long lasting currents but block neurotransmitter vesicle anchoring in voltage-dependent P/Q-type Ca2+ channels. J Biol Chem 285:21750-67 (2010). WB ; Human . Read more (PubMed: 20452978) »

See 1 Publication for this product

Product Wall

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Western blot
Sample Rat Recombinant protein (recombinant protein from e.Coli)
Loading amount 10 µg
Specification recombinant protein from e.Coli
Gel Running Conditions Reduced Denaturing
Blocking step Milk as blocking agent for 15 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 4°C
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提交于 Oct 23 2008

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"