Anti-CACNB1抗体[S7-18] (ab85020)

概述

  • 产品名称Anti-CACNB1抗体[S7-18]
    参阅全部 CACNB1 一抗
  • 描述
    小鼠单克隆抗体[S7-18] to CACNB1
  • 特异性No cross reactivity against CACNB4.
  • 经测试应用适用于: WB, ICC/IF, IHC-Fr, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
    预测可用于: Rabbit, Cow
  • 免疫原

    Synthetic peptide:

    PMEVFDPSPQGKYSKR

    , corresponding to amino acids 19-34 of Rat CACNB1 (NP_059042).

  • 阳性对照
    • Rat brain lysate.

性能

应用

Our Abpromise guarantee covers the use of ab85020 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 10 µg/ml. Predicted molecular weight: 66 kDa.
ICC/IF Use a concentration of 1 - 10 µg/ml.
IHC-Fr Use a concentration of 0.1 - 1 µg/ml.
IHC-P Use a concentration of 0.1 - 1 µg/ml.

靶标

  • 功能The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
  • 组织特异性Isoform 1 and isoform 3 are expressed in brain, heart, spleen, central nervous system and neuroblastoma cells. Isoform 2 is expressed in skeletal muscle.
  • 序列相似性Belongs to the calcium channel beta subunit family.
    Contains 1 SH3 domain.
  • 细胞定位Cell membrane > sarcolemma.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CAB1 antibody
    • CACB1_HUMAN antibody
    • CACNB1 antibody
    • CACNLB1 antibody
    • Calcium channel L type beta 1 polypeptide antibody
    • Calcium channel voltage dependent beta 1 subunit antibody
    • Calcium channel voltage-dependent subunit beta 1 antibody
    • CCHLB1 antibody
    • Dihydropyridine sensitive L type calcium channel beta 1 subunit antibody
    • MGC41896 antibody
    • Voltage dependent L type calcium channel beta 1 subunit antibody
    • Voltage-dependent L-type calcium channel subunit beta-1 antibody
    see all

Anti-CACNB1 antibody [S7-18] 图像

  • ab85020 staining CACNB1 in human hippocampus tissue section by IHC-P. Bouin's fixed and paraffin-embedded tissue sections were used.

Anti-CACNB1 antibody [S7-18] (ab85020)参考文献

ab85020 has not yet been referenced specifically in any publications.

Product Wall

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Western blot
Sample Mouse Tissue lysate - other (Hippocampal synaptosome preparation)
Loading amount 5 µg
Specification Hippocampal synaptosome preparation
Gel Running Conditions Reduced Denaturing (Bis Tris 4-12%)
Blocking step Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
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提交于 Feb 18 2010

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"