Anti-CABP抗体- Carboxyterminal end (ab75949)


  • 产品名称Anti-CABP抗体- Carboxyterminal end
    参阅全部 CABP 一抗
  • 描述
    兔多克隆抗体to CABP - Carboxyterminal end
  • 经测试应用适用于: IHC-P, WB, ELISAmore details
  • 种属反应性
    与反应: Mouse, Human
  • 阳性对照
    • Mouse cerebellum tissue lysate



Our Abpromise guarantee covers the use of ab75949 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/10 - 1/50.
WB 1/50 - 1/100. Predicted molecular weight: 26 kDa.
ELISA 1/1000.


  • 功能Modulates calcium-dependent activity of inositol 1,4,5-triphosphate receptors (ITPRs). Inhibits agonist-induced intracellular calcium signaling. Enhances inactivation and does not support calcium-dependent facilitation of voltage-dependent P/Q-type calcium channels. Causes calcium-dependent facilitation and inhibits inactivation of L-type calcium channels by binding to the same sites as calmodulin in the C-terminal domain of CACNA1C, but resulting in an opposit effects on channel function. Suppresses the calcium-dependent inactivation of CACNA1D (By similarity). Inhibits TRPC5 channels. Prevents NMDA receptor-induced cellular degeneration.
  • 组织特异性Retina and brain. Somatodendritic compartment of neurons. Calbrain was found exclusively in brain where it is abundant in the hippocampus, habenular area in the epithalamus and in the cerebellum.
  • 序列相似性Contains 4 EF-hand domains.
  • 结构域EF-1 binds magnesium constitutively under physiological conditions, EF-3 and EF-4 bind calcium cooperatively and EF-2 binds neither calcium nor magnesium.
  • 翻译后修饰Phosphorylated. The phosphorylation regulates the activity.
  • 细胞定位Cytoplasm > cell cortex. Cell membrane. S-CaBP1 is localized at or near the plasma membrane; Cytoplasm > cytoskeleton. Cytoplasm > perinuclear region. Cell membrane. Golgi apparatus. Cell junction > synapse > postsynaptic cell membrane > postsynaptic density. L-CaBP1 is associated most likely with the cytoskeletal structures, whereas S-CaBP1 is localized at or near the plasma membrane and Cytoplasm > cytoskeleton. L-CaBP1 is associated most likely with the cytoskeletal structures.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CABP 1 antibody
    • CaBP1 antibody
    • CABP1_HUMAN antibody
    • Calbrain antibody
    • Calcium binding protein 1 antibody
    • Calcium binding protein 5 antibody
    • Calcium-binding protein 1 antibody
    • Caldendrin antibody
    • HCALB BR antibody
    • HCALB_BR antibody
    see all

Anti-CABP antibody - Carboxyterminal end 图像

  • Anti-CABP antibody - Carboxyterminal end (ab75949) at 1/60 dilution + mouse cerebellum tissue lysate at 35 µg

    Predicted band size : 26 kDa
    Observed band size : 26 kDa
  • ab75949 at 1/50 dilution staining CABP - Carboxyterminal in human brain tissue section by Immunohistochemistry (Formalin/ PFA fixed paraffin-embedded sections). A peroxidase conjugated secondary antibody was used followed by DAB staining.

Anti-CABP antibody - Carboxyterminal end (ab75949)参考文献

ab75949 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab75949.
Please use the links above to contact us or submit feedback about this product.