Anti-C6抗体- N-terminal (ab92622)

概述

  • 产品名称Anti-C6抗体- N-terminal
    参阅全部 C6 一抗
  • 描述
    兔多克隆抗体to C6 - N-terminal
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide selected from the N terminal region of Human C6 conjugated to KLH.

  • 阳性对照
    • MDA-MB231 cell line lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明Purified through a protein A column, followed by peptide affinity purification.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab92622 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
  • 应用说明ELISA: 1/1000.
    WB: 1/100 - 1/500. Predicted molecular weight: 105 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
    • 疾病相关Defects in C6 are the cause of complement component 6 deficiency (C6D) [MIM:612446]. A rare defect of the complement classical pathway associated with susceptibility to severe recurrent infections, predominantly by Neisseria gonorrhoeae or Neisseria meningitidis.
    • 序列相似性Belongs to the complement C6/C7/C8/C9 family.
      Contains 1 EGF-like domain.
      Contains 2 Kazal-like domains.
      Contains 1 LDL-receptor class A domain.
      Contains 1 MACPF domain.
      Contains 2 Sushi (CCP/SCR) domains.
      Contains 3 TSP type-1 domains.
    • 翻译后修饰All cysteine residues are assumed to be cross-linked to one another. Individual modules containing an even number of conserved cysteine residues are supposed to have disulfide linkages only within the same module.
    • 细胞定位Secreted.
    • Information by UniProt
    • 数据库链接
    • 别名
      • AW111623 antibody
      • C6 antibody
      • CO6_HUMAN antibody
      • Complement component 6 antibody
      • Complement component C6 antibody
      see all

    Anti-C6 antibody - N-terminal 图像

    • Anti-C6 antibody - N-terminal (ab92622) at 1/100 dilution + MDA-MB231 cell line lysate at 35 µg

      Predicted band size : 105 kDa

    Anti-C6 antibody - N-terminal (ab92622)参考文献

    ab92622 has not yet been referenced specifically in any publications.

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