概述

  • 产品名称Anti-C6抗体[13H5]
    参阅全部 C6 一抗
  • 描述
    小鼠单克隆抗体[13H5] to C6
  • 经测试应用适用于: WB, IP, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    C6 protein purified from human plasma.

  • 阳性对照
    • Human plasma

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.03% Sodium Azide
    Constituents: 50% Glycerol, 0.01% BSA, HEPES, 0.15M Sodium chloride
  • Concentration information loading...
  • 克隆单克隆
  • 克隆编号13H5
  • 同种型IgG2b
  • 轻链类型kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab71942 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
IP
ELISA
  • 应用说明ELISA: Use at an assay dependent dilution.
    IP: Use 2µl.
    WB: 1/2000. Detects a band of approximately 105 kDa (predicted molecular weight: 105 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
    • 疾病相关Defects in C6 are the cause of complement component 6 deficiency (C6D) [MIM:612446]. A rare defect of the complement classical pathway associated with susceptibility to severe recurrent infections, predominantly by Neisseria gonorrhoeae or Neisseria meningitidis.
    • 序列相似性Belongs to the complement C6/C7/C8/C9 family.
      Contains 1 EGF-like domain.
      Contains 2 Kazal-like domains.
      Contains 1 LDL-receptor class A domain.
      Contains 1 MACPF domain.
      Contains 2 Sushi (CCP/SCR) domains.
      Contains 3 TSP type-1 domains.
    • 翻译后修饰All cysteine residues are assumed to be cross-linked to one another. Individual modules containing an even number of conserved cysteine residues are supposed to have disulfide linkages only within the same module.
    • 细胞定位Secreted.
    • Information by UniProt
    • 数据库链接
    • 别名
      • AW111623 antibody
      • C6 antibody
      • CO6_HUMAN antibody
      • Complement component 6 antibody
      • Complement component C6 antibody
      see all

    Anti-C6 antibody [13H5] 图像

    • All lanes : Anti-C6 antibody [13H5] (ab71942) at 1/2000 dilution

      Lane 1 : C6 protein isolated from human plasma
      Lane 2 : Human plasma at 0.5 µl


      Predicted band size : 105 kDa
      Observed band size : 105 kDa

    Anti-C6 antibody [13H5] (ab71942)参考文献

    This product has been referenced in:

    See 1 Publication for this product

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