概述

  • 产品名称Anti-C5R1抗体[P12/1]
    参阅全部 C5R1 一抗
  • 描述
    小鼠单克隆抗体[P12/1] to C5R1
  • 特异性This antibody recognises the C5R1 receptor but does not inhibit the binding of C5a to its receptor.
  • 经测试应用适用于: Flow Cyt, WB, IHC-Fr, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide:

    MNSFNYTTPDYGHYDDKDTLDLNTPVDKTSN

    , corresponding to N terminal amino acids 1-31 of Human C5R1.

性能

应用

Our Abpromise guarantee covers the use of ab24036 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt 1/50 - 1/100. Use 10µl of this working solution to label 5 x 105 cells in 100µl



ab170191-Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
WB Use at an assay dependent concentration. Predicted molecular weight: 39 kDa.
IHC-Fr Use at an assay dependent concentration.
IHC-P 1/200.

靶标

  • 功能Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.
  • 序列相似性Belongs to the G-protein coupled receptor 1 family.
  • 翻译后修饰Sulfation plays a critical role in the association of the receptor with C5a, but no significant role in the ability of the receptor to transduce a signal and mobilize calcium in response to a small peptide agonist.
  • 细胞定位Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ANAPHYLATOXIN RECEPTOR antibody
    • C5a anaphylatoxin chemotactic receptor antibody
    • C5a anaphylatoxin receptor antibody
    • C5A antibody
    • C5a ligand antibody
    • C5a-R antibody
    • C5aR antibody
    • C5AR_HUMAN antibody
    • c5ar1 antibody
    • C5R1 antibody
    • CD88 antibody
    • CD88 antigen antibody
    • Complement component 5 receptor 1 antibody
    • Complement component 5 receptor 2 antibody
    • Complement component 5a receptor 1 antibody
    see all

Anti-C5R1 antibody [P12/1] (ab24036)参考文献

This product has been referenced in:
  • Oppermann M  et al. Probing the human receptor for C5a anaphylatoxin with site-directed antibodies. Identification of a potential ligand binding site on the NH2-terminal domain. J Immunol 151:3785-94 (1993). Read more (PubMed: 8376805) »

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab24036.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"