概述

  • 产品名称
    Anti-C5R1抗体[10/92] (Biotin)
    参阅全部 C5R1 一抗
  • 描述
    大鼠单克隆抗体[10/92] to C5R1 (Biotin)
  • 偶联物
    Biotin
  • 特异性
    Clone 10/92 does not block the binding of the C5a to murine CD88.
  • 经测试应用
    适用于: Flow Cyt, IHC-Frmore details
  • 种属反应性
    与反应: Mouse
  • 免疫原

    RBL-2H3 transfected cells expressing murine C5R1.

性能

应用

Our Abpromise guarantee covers the use of ab54378 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt 1/1. ab18445-Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
IHC-Fr Use at an assay dependent concentration.

靶标

  • 功能
    Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.
  • 序列相似性
    Belongs to the G-protein coupled receptor 1 family.
  • 翻译后修饰
    Sulfation plays a critical role in the association of the receptor with C5a, but no significant role in the ability of the receptor to transduce a signal and mobilize calcium in response to a small peptide agonist.
  • 细胞定位
    Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ANAPHYLATOXIN RECEPTOR antibody
    • C5a anaphylatoxin chemotactic receptor antibody
    • C5a anaphylatoxin receptor antibody
    • C5A antibody
    • C5a ligand antibody
    • C5a-R antibody
    • C5aR antibody
    • C5AR_HUMAN antibody
    • c5ar1 antibody
    • C5R1 antibody
    • CD88 antibody
    • CD88 antigen antibody
    • Complement component 5 receptor 1 antibody
    • Complement component 5 receptor 2 antibody
    • Complement component 5a receptor 1 antibody
    see all

文献

This product has been referenced in:
  • Copland DA  et al. Systemic and local anti-C5 therapy reduces the disease severity in experimental autoimmune uveoretinitis. Clin Exp Immunol 159:303-14 (2010). IHC-Fr ; Mouse . Read more (PubMed: 20002447) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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