Anti-C5a / C5a des Arg抗体[2952] (ab11878)

概述

  • 产品名称Anti-C5a / C5a des Arg抗体[2952]
    参阅全部 C5a / C5a des Arg 一抗
  • 描述
    小鼠单克隆抗体[2952] to C5a / C5a des Arg
  • 特异性This antibody reacts with a neo-epitope (des-Arg) on C5a that is formed upon cleavage of C5 into C5a and C5b. It will detect C5a and C5a des-Arg (Not C5).
  • 经测试应用适用于: IHC-Fr, Functional Studies, IHC-P, ELISA, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    ISHKDMQLG

    (C5a amino acid 65-73)

  • 阳性对照
    • Human Granulocytes

性能

应用

Our Abpromise guarantee covers the use of ab11878 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-Fr Use at an assay dependent concentration.
Functional Studies Use at an assay dependent concentration.
IHC-P Use at an assay dependent concentration.
ELISA Use at an assay dependent concentration.
WB Use at an assay dependent concentration.

靶标

  • 相关性C5 is involved in the activation of the lytic pathway within the complement system, which is an important factor in innate immunity.
  • 数据库链接
  • 别名
    • Anaphylatoxin C5a analog antibody
    • C5 antibody
    • C5a anaphylatoxin antibody
    • Complement C5 precursor antibody
    • Complement component 5 antibody
    • Complement component C5a antibody
    • CPAMD 4 antibody
    • CPAMD4 antibody
    • MGC142298 antibody
    see all

Anti-C5a / C5a des Arg antibody [2952] 图像

  • ELISA with ab11876 as capture antibody at 1/100, ab11878 as detection antibody at 1/250, diluted in carbonate buffer or PBS. Dilutions of commercial C5a were used as the standard.

    See Abreview

Anti-C5a / C5a des Arg antibody [2952] (ab11878)参考文献

This product has been referenced in:
  • Ecker SM  et al. Aqueous cytokine and growth factor levels do not reliably reflect those levels found in the vitreous. Mol Vis 17:2856-63 (2011). WB ; Human . Read more (PubMed: 22128233) »
  • Nozaki M  et al. Drusen complement components C3a and C5a promote choroidal neovascularization. Proc Natl Acad Sci U S A 103:2328-33 (2006). IHC-Fr ; Mouse, Human . Read more (PubMed: 16452172) »

See all 2 Publications for this product

Product Wall

Abcam guarantees this product to work in the species/application used in this Abreview.
Application ELISA
Sample Human Serum (Serum or EDTA plasma)
Specification Serum or EDTA plasma
Type Sandwich (Detection)
Username

Abcam user community

Verified customer

提交于 Nov 02 2007

Thank you for your e-mail regarding ab11878 monoclonal antibody to mouse C5a, clone 2952. We regret to inform you that we never heard about any problems by detection of C5a on nitrocellulose membranes. Can your customer provide us some more informat...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"