概述

  • 产品名称Anti-C5 / C5b抗体
    参阅全部 C5 / C5b 一抗
  • 描述
    兔多克隆抗体to C5 / C5b
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 50 - 150 of Human C5/C5b.

    (Peptide available as ab46170.)

  • 阳性对照
    • This antibody gave a positive signal in purified human C5 protein.

性能

应用

Our Abpromise guarantee covers the use of ab46171 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 mg/ml. Detects a band of approximately 74 kDa (predicted molecular weight: 188 kDa).

靶标

  • 相关性C5 is synthesised in the liver as a single polypeptide chain. Before secretion the molecule is glycosylated and secreted into plasma as a 190kDa glycoprotein consisting of a disulphide linked alpha-chain (115kDa) and beta-chain (75kDa). C5 precursor is first processed by the removal of 4 basic residues, forming two chains, beta and alpha, linked by a disulfide bond. C5 convertase activates C5 by cleaving the alpha chain, releasing C5a anaphylatoxin and generating C5b (beta chain + alpha' chain).
  • 细胞定位Secreted
  • 数据库链接
  • 别名
    • C5 antibody
    • Complement C5 antibody
    • Complement component 5 antibody
    • CPAMD4 antibody

Anti-C5 / C5b antibody 图像

  • Anti-C5 / C5b antibody (ab46171) at 1 µg/ml + Human Complement C5 Protein at 0.1 µg

    Secondary
    Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution

    Performed under reducing conditions.

    Predicted band size : 188 kDa
    Observed band size : 74 kDa (why is the actual band size different from the predicted?)

Anti-C5 / C5b antibody (ab46171)参考文献

ab46171 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab46171.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"