Anti-C5 / C5b抗体[568] (ab11879)

概述

  • 产品名称Anti-C5 / C5b抗体[568]
    参阅全部 C5 / C5b 一抗
  • 描述
    小鼠单克隆抗体[568] to C5 / C5b
  • 特异性This antibody reacts with an epitope on C5 and on C5b.
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Unfortunately, this information is considered to be commercially sensitive

性能

应用

Our Abpromise guarantee covers the use of ab11879 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent dilution. Use under non reducing condition. Predicted molecular weight: 188.3 kDa.

靶标

  • 相关性C5 is synthesised in the liver as a single polypeptide chain. Before secretion the molecule is glycosylated and secreted into plasma as a 190kDa glycoprotein consisting of a disulphide linked alpha-chain (115kDa) and beta-chain (75kDa). C5 precursor is first processed by the removal of 4 basic residues, forming two chains, beta and alpha, linked by a disulfide bond. C5 convertase activates C5 by cleaving the alpha chain, releasing C5a anaphylatoxin and generating C5b (beta chain + alpha' chain).
  • 细胞定位Secreted
  • 数据库链接
  • 别名
    • C5 antibody
    • Complement C5 antibody
    • Complement component 5 antibody
    • CPAMD4 antibody

Anti-C5 / C5b antibody [568] (ab11879)参考文献

ab11879 has not yet been referenced specifically in any publications.

Product Wall

ab11879 is only able to recognize whole C5 or C5b as the epitope lies in the C5b region. Therefore, there should not be any cross-reactivity with C5a.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"