概述

  • 产品名称
    Anti-C4 binding protein抗体
    参阅全部 C4 binding protein 一抗
  • 描述
    羊多克隆抗体to C4 binding protein
  • 经测试应用
    适用于: IHC-Frmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Human C4BP purified from plasma

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液
    Preservative: 0.09% Sodium Azide
    Constituents: 0.1% EACA, 0.01% Benzamidine, Glycine buffered saline, 1mM EDTA, pH 7.4
  • Concentration information loading...
  • 纯度
    Ion Exchange Chromatography
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab53894 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-Fr 1/20 - 1/200.

靶标

  • 功能
    Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. It also interacts with anticoagulant protein S and with serum amyloid P component. The beta chain binds protein S.
  • 序列相似性
    Contains 3 Sushi (CCP/SCR) domains.
  • 细胞定位
    Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • C4b binding protein beta chain antibody
    • C4b-binding protein beta chain antibody
    • C4BP antibody
    • C4BPB antibody
    • C4BPB_HUMAN antibody
    • Complement component 4 binding protein beta antibody
    • Complement component 4 binding protein beta chain antibody
    • Complement component 4-binding protein beta antibody
    • OTTHUMP00000034288 antibody
    • OTTHUMP00000034289 antibody
    • OTTHUMP00000034375 antibody
    • OTTHUMP0000003474 antibody
    • Proline rich protein antibody
    • PRP antibody
    see all

文献

This product has been referenced in:
  • Yuste J  et al. Roles of the alternative complement pathway and C1q during innate immunity to Streptococcus pyogenes. J Immunol 176:6112-20 (2006). Flow Cyt . Read more (PubMed: 16670320) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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