Anti-C4 binding protein抗体[10-07] (ab118876)

概述

  • 产品名称Anti-C4 binding protein抗体[10-07]
    参阅全部 C4 binding protein 一抗
  • 描述
    小鼠单克隆抗体[10-07] to C4 binding protein
  • 特异性ab118876 recognizes complement C4 binding protein.
  • 经测试应用适用于: ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length native Human C4 binding protein (purified).

  • 阳性对照
    • Human liver tissue
  • 常规说明


    There are three variants of C4 binding protein, composed of alpha and beta chains. The predominant form is a 570 kD complex of 7 alpha chains and 1 beta chain. The other complexes formed are a 530 kD homoheptamer of alpha chains or a 500 kD complex of 6 alpha chains and 1 beta chain. C4 binding protein is expressed in the blood serum.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液pH: 8.40
    Preservative: 0.1% Sodium azide
    Constituent: 99% Borate buffered saline
  • Concentration information loading...
  • 纯度Protein A purified
  • Primary antibody说明There are three variants of C4 binding protein, composed of alpha and beta chains. The predominant form is a 570 kD complex of 7 alpha chains and 1 beta chain. The other complexes formed are a 530 kD homoheptamer of alpha chains or a 500 kD complex of 6 alpha chains and 1 beta chain. C4 binding protein is expressed in the blood serum.
  • 克隆单克隆
  • 克隆编号10-07
  • 同种型IgG2b
  • 研究领域

相关产品

应用

Our Abpromise guarantee covers the use of ab118876 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent concentration.
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. It also interacts with anticoagulant protein S and with serum amyloid P component. The beta chain binds protein S.
  • 序列相似性Contains 3 Sushi (CCP/SCR) domains.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • C4b binding protein beta chain antibody
    • C4b-binding protein beta chain antibody
    • C4BP antibody
    • C4BPB antibody
    • C4BPB_HUMAN antibody
    • Complement component 4 binding protein beta antibody
    • Complement component 4 binding protein beta chain antibody
    • Complement component 4-binding protein beta antibody
    • OTTHUMP00000034288 antibody
    • OTTHUMP00000034289 antibody
    • OTTHUMP00000034375 antibody
    • OTTHUMP0000003474 antibody
    • Proline rich protein antibody
    • PRP antibody
    see all

Anti-C4 binding protein antibody [10-07] 图像

  • ab118876, at 5 µg/ml, staining C4 binding protein in formalin fixed, paraffin embedded Human liver tissue by Immunohistochemistry.

Anti-C4 binding protein antibody [10-07] (ab118876)参考文献

ab118876 has not yet been referenced specifically in any publications.

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