概述

  • 产品名称Anti-C20orf20抗体
    参阅全部 C20orf20 一抗
  • 描述
    兔多克隆抗体to C20orf20
  • 特异性This antibody reacts with C20orf20
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Cow
  • 免疫原

    A region within synthetic peptide: LSTMYDMQAL HESEILPFPN PERNFVLPEE IIQEVREGKV MIEEEMKEEM, corresponding to amino acids 81-130 of Human C20orf20

  • 阳性对照
    • Transfected 293T cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab50873 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/312500.

Titre using peptide based assay: 1/312500.

WB Use a concentration of 0.25 µg/ml. Detects a band of approximately 29 kDa (predicted molecular weight: 22 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage.
  • 序列相似性Belongs to the EAF7 family.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • C20orf20 antibody
    • Chromosome 20 open reading frame 20 antibody
    • Eaf7 antibody
    • FLJ10914 antibody
    • MRG (MORF4 related gene) binding protein antibody
    • MRG binding protein antibody
    • MRG-binding protein antibody
    • MRG/MORF4L binding protein antibody
    • MRG15BP antibody
    • Mrgbp antibody
    • MRGBP_HUMAN antibody
    • OTTHUMP00000031512 antibody
    • URCC4 antibody
    see all

Anti-C20orf20 antibody 图像

  • Anti-C20orf20 antibody (ab50873) at 0.25 µg/ml + Transfected 293T cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 22 kDa
    Observed band size : 29 kDa (why is the actual band size different from the predicted?)

Anti-C20orf20 antibody (ab50873)参考文献

ab50873 has not yet been referenced specifically in any publications.

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