产品名称 Anti-C1s抗体 参阅全部 C1s 一抗
ELISA, WB, IHC-P more details
Synthetic peptide derived from a region corresponding to internal residues of Human C1s
COLO, Jurkat cells and Human breast carcinoma tissue
存放说明 Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
存储溶液 Preservative: 0.02% Sodium Azide
Constituents: 50% Glycerol, PBS (without Mg 2+ and Ca 2+),150mM Sodium chloride, pH 7.4
Concentration information loading...
纯度 Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
应用说明 ELISA: 1/40000.
IHC-P: 1/50 - 1/100.
WB: 1/500 - 1/1000. Predicted molecular weight: 77 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
功能 C1s B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4.
疾病相关 Defects in C1S are the cause of complement component C1s deficiency (C1SD) [MIM:613783]. A rare defect resulting in C1 deficiency and impaired activation of the complement classical pathway. C1 deficiency generally leads to severe immune complex disease with features of systemic lupus erythematosus and glomerulonephritis.
序列相似性 Belongs to the peptidase S1 family. Contains 2 CUB domains. Contains 1 EGF-like domain. Contains 1 peptidase S1 domain. Contains 2 Sushi (CCP/SCR) domains.
翻译后修饰 The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains.
Information by UniProt
Basic proline rich peptide IB 1 antibody
C1 esterase antibody
Anti-C1s antibody 图像
Western blot - C1s antibody (ab92706)
All lanes : Anti-C1s antibody (ab92706) at 1/500 dilution Lane 1 : COLO cells
(without peptide) Lane 2 : Jurkat cells
(without peptide) Lane 3 : COLO cells
(with peptide) Lysates/proteins at 30 µg per lane. Predicted band size : 77 kDa
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - C1s antibody (ab92706)
ab92706 at 1/50 dilution, staining C1s in Human breast carcinoma paraffin-embedded tissue by immunohistochemistry. Right hand image with peptide and left hand image without peptide.
Anti-C1s antibody (ab92706)参考文献
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"