概述

  • 产品名称
  • 描述
    兔多克隆抗体to C1RL
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 160-190 of Human C1RL (NP_057630.2).

  • 阳性对照
    • Jurkat cell line lysates.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • 存储溶液
    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 纯化说明
    ab123797 is purified through a protein A column, followed by peptide affinity purification.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab123797 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 53 kDa.

靶标

  • 功能
    Mediates the proteolytic cleavage of HP/haptoglobin in the endoplasmic reticulum.
  • 组织特异性
    Highly expressed in placenta, liver, kidney, pancreas, moderately in lung, spleen, prostate, ovary, colon, and PBL, and weakly in heart, skeletal muscle, thymus, testis, and small intestine. Expressed in PC-3 (prostate adenocarcinoma) and SK-OV-3 (ovary adenocarcinoma) cells, but not in LoVo and HT-29 (colon adenocarcinoma), SMMC7721 (hepatocellular carcinoma), CaoV-3 (ovary adenocarcinoma), HeLa (cervix epithelioid carcinoma), MCF-7 (breast adenocarcinoma), U-251MG (glioma) or A-549 (lung carcinoma) cells. Widely expressed in myeloid leukemia cell lines, including K-562 (chronic myelogenous leukemia), THP-1 (myelomonocytic leukemia), HL-60 and NB4 (promyelocytic leukemia), and KG-1 (acute myelogenous leukemia) cells. Expressed mainly in the liver and in serum (at protein level).
  • 序列相似性
    Belongs to the peptidase S1 family.
    Contains 1 CUB domain.
    Contains 1 peptidase S1 domain.
  • 细胞定位
    Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • C1r like protein antibody
    • C1r like serine protease analog antibody
    • C1r like serine protease analog protein antibody
    • C1r LP antibody
    • C1r-like protein antibody
    • C1r-like serine protease analog protein antibody
    • C1r-LP antibody
    • C1rl antibody
    • C1RL_HUMAN antibody
    • C1RL1 antibody
    • C1RLP antibody
    • CLSPa antibody
    • complement C1r like proteinase antibody
    • Complement C1r subcomponent-like protein antibody
    • Complement component 1 r subcomponent like antibody
    see all

Anti-C1RL antibody 图像

  • Anti-C1RL antibody (ab123797) at 1/100 dilution + Jurkat cell line lysates at 35 µg

    Predicted band size : 53 kDa

实验方案

Anti-C1RL antibody (ab123797)参考文献

ab123797 has not yet been referenced specifically in any publications.

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