产品名称 Anti-C1r抗体 参阅全部 C1r 一抗
特异性 ab72648 detects a fragment (light chain) of activated C1r resulting from cleavage adjacent to Ile464.
WB, ELISA more details
Synthetic peptide derived from human C1r.
Extracts from 293 cells treated with etoposide (25uM, 1hour) and A549 cells treated with etoposide (25uM, 24hours).
存放说明 Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
存储溶液 Preservative: 0.02% Sodium Azide
Constituents: 50% Glycerol, PBS (without Mg 2+ and Ca 2+), 150mM Sodium chloride, pH 7.4
Concentration information loading...
纯度 Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Detects a band of approximately 29 kDa (predicted molecular weight: 29 kDa).
功能 C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system.
序列相似性 Belongs to the peptidase S1 family. Contains 2 CUB domains. Contains 1 EGF-like domain. Contains 1 peptidase S1 domain. Contains 2 Sushi (CCP/SCR) domains.
翻译后修饰 The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains.
Information by UniProt
C1 R antibody
Anti-C1r antibody 图像
Western blot - C1r antibody (ab72648)
All lanes : Anti-C1r antibody (ab72648) at 1/500 dilution Lane 1 : Extracts from 293 cells treated
with etoposide (25uM, 1hour) Lane 2 : Extracts from A549 cells treated with
etoposide (25uM, 24hours) Lane 3 : Extracts from 293 cells treated
with etoposide (25uM, 1hour) with immunising peptide at 5 µg Lysates/proteins at 5 µg per lane. Predicted band size : 29 kDa Observed band size : 29 kDa Additional bands at : 19 kDa,40 kDa,60 kDa. We are unsure as to the identity of these extra bands.
Anti-C1r antibody (ab72648)参考文献
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"