产品名称 Anti-C1r抗体 参阅全部 C1r 一抗
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Non Human Primates
Synthetic peptide conjugated to KLH derived from within residues 1 - 100 of Human C1r.
(Peptide available as
This antibody gave a positive signal in Human plasma (total protein)
存放说明 Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
存储溶液 Preservative: 0.02% Sodium Azide
Constituents: 1% BSA, PBS, pH 7.4
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纯度 Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 µg/ml. Detects a band of approximately 90 kDa (predicted molecular weight: 80 kDa).
功能 C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system.
序列相似性 Belongs to the peptidase S1 family. Contains 2 CUB domains. Contains 1 EGF-like domain. Contains 1 peptidase S1 domain. Contains 2 Sushi (CCP/SCR) domains.
翻译后修饰 The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains.
Information by UniProt
C1 R antibody
Anti-C1r antibody 图像
Western blot - C1r antibody (ab66751)
All lanes : Anti-C1r antibody (ab66751) at 1 µg/ml Lane 1 : Human Plasma Total Protein Lysate at 2 µg Lane 2 : Human Plasma Total Protein Lysate at 5 µg Lane 3 : Human Plasma Total Protein Lysate at 10 µg Secondary Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) Performed under reducing conditions. Predicted band size : 80 kDa Observed band size : 90 kDa ( why is the actual band size different from the predicted?) Exposure time : 1 minute
Anti-C1r antibody (ab66751)参考文献
This product has been referenced in:
et al. Periodontal Ehlers-Danlos Syndrome Is Caused by Mutations in C1R and C1S, which Encode Subcomponents C1r and C1s of Complement. Am J Hum Genet 99:1005-1014 (2016).
Read more (PubMed: 27745832) »
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"