概述

  • 产品名称Anti-C1orf19抗体
    参阅全部 C1orf19 一抗
  • 描述
    兔多克隆抗体to C1orf19
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse
    预测可用于: Rat, Rabbit, Guinea pig, Cow, Cat, Dog, Human, Pig
  • 免疫原

    Synthetic peptide corresponding to a region within C-terminal amino acids 109-158 (

    ASLSHNRIREILKASRKLQGDPELPMSFTLAIVESDSTIVYYKLTDGFML

    ) of Mouse C1orf19 (NP_079953).

  • 阳性对照
    • Mouse Spleen lysate

性能

应用

Our Abpromise guarantee covers the use of ab122934 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 19 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3' end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3' end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events.
  • 组织特异性Widely expressed. Highly expressed in testis and uterus.
  • 序列相似性Belongs to the SEN15 family.
  • 细胞定位Nucleus. Nucleus > nucleolus. May be transiently localized in the nucleolus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Chromosome 1 open reading frame 19 antibody
    • Chromosome 1 open reading frame 19, isoform CRA_c antibody
    • HsSen15 antibody
    • sen15 antibody
    • SEN15 homolog antibody
    • SEN15_HUMAN antibody
    • tRNA intron endonuclease Sen15 antibody
    • tRNA splicing endonuclease 15 homolog (S. cerevisiae) antibody
    • tRNA splicing endonuclease subunit Sen15 antibody
    • tRNA-intron endonuclease SEN15 antibody
    • tRNA-splicing endonuclease subunit SEN15 antibody
    • Tsen15 antibody
    see all

Anti-C1orf19 antibody 图像

  • Anti-C1orf19 antibody (ab122934) at 1 µg/ml + Mouse Spleen lysate at 10 µg

    Predicted band size : 19 kDa

Anti-C1orf19 antibody (ab122934)参考文献

ab122934 has not yet been referenced specifically in any publications.

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