概述

  • 产品名称Anti-C1orf187抗体
    参阅全部 C1orf187 一抗
  • 描述
    兔多克隆抗体to C1orf187
  • 特异性At least three isoforms of C1orf187 are known to exist; ab117452 will detect the two shorter isoforms. ab117452 is predicted to not cross-react with RILP.
  • 经测试应用适用于: ICC/IF, WB, IHC-P, ICCmore details
  • 种属反应性
    与反应: Mouse, Rat
    预测可用于: Human
  • 免疫原

    Synthetic peptide corresponding to 17 amino acids from the C terminal of Human C1orf187 (BAG80561).

  • 阳性对照
    • Rat cerebellum tissue lysate.
  • 常规说明Avoid repeated freeze thaw cycles and exposure to prolonged high temperatures.

性能

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应用

Our Abpromise guarantee covers the use of ab117452 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 38 kDa.
IHC-P Use at an assay dependent concentration.
ICC Use a concentration of 5 µg/ml.

靶标

  • 功能Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.
  • 序列相似性Belongs to the draxin family.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AGPA3119 antibody
    • Chromosome 1 open reading frame 187 antibody
    • Dorsal inhibitory axon guidance protein antibody
    • Dorsal repulsive axon guidance protein antibody
    • DRAXI_HUMAN antibody
    • Draxin antibody
    • FLJ34999 antibody
    • MGC117222 antibody
    • Neucrin antibody
    • OTTHUMP00000002262 antibody
    • UNQ3119 antibody
    see all

Anti-C1orf187 antibody 图像

  • Immunofluorescence of C1orf187 in mouse brain tissue with ab117452 at 20 ug/mL.
  • Anti-C1orf187 antibody (ab117452) at 1 µg/ml + Rat cerebellum tissue lysate at 15 µg

    Predicted band size : 38 kDa
  • Immunohistochemical analysis of mouse brain tissue, staining C1orf187 with ab117452 at 5 µg/ml.

Anti-C1orf187 antibody (ab117452)参考文献

ab117452 has not yet been referenced specifically in any publications.

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