概述

  • 产品名称Anti-C1orf149抗体
  • 描述
    兔多克隆抗体to C1orf149
  • 经测试应用适用于: ELISA, WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cow, Zebrafish
  • 免疫原

    Synthetic peptide (Human)

  • 阳性对照
    • Jurkat cell lysate; human kidney tissue.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab42472 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent concentration.

ELISA titre using peptide based assay: 1:312500.

WB Use a concentration of 0.5 µg/ml. Detects a band of approximately 24 kDa (predicted molecular weight: 22 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
IHC-P Use a concentration of 4 - 8 µg/ml.

靶标

  • 功能Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.
  • 疾病相关A chromosomal aberration involving MEAF6 may be a cause of endometrial stromal tumors. Translocation t(1;6)(p34;p21) with PHF1.
  • 序列相似性Belongs to the EAF6 family.
  • 细胞定位Nucleus, nucleolus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CDABP0189 antibody
    • Chromatin modification-related protein MEAF6 antibody
    • Chromosome 1 open reading frame 149 antibody
    • Eaf6 antibody
    • EAF6_HUMAN antibody
    • Esa1-associated factor 6 homolog antibody
    • FLJ11730 antibody
    • hEAF6 antibody
    • Hypothetical protein LOC64769 antibody
    • MEAF6 antibody
    • MYST/Esa1-associated factor 6 antibody
    • NY SAR 91 antibody
    • Protein EAF6 homolog antibody
    • RP3 423B22.2 antibody
    • Sarcoma antigen NY SAR 91 antibody
    • Sarcoma antigen NY-SAR-91 antibody
    see all

Anti-C1orf149 antibody 图像

  • Anti-C1orf149 antibody (ab42472) at 0.5 µg/ml + Jurkat cell lyste at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 22 kDa
    Observed band size : 24 kDa (why is the actual band size different from the predicted?)
  • ab42472 at 8µg/ml staining human kidney for C1orf149. Arrows indicate staining of epithelial cells of collecting tubules.

Anti-C1orf149 antibody (ab42472)参考文献

ab42472 has not yet been referenced specifically in any publications.

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