概述

  • 产品名称
  • 描述
    山羊多克隆抗体to C1D
  • 经测试应用
    适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide:

    C-SKNASKVANKGKSKS

    , corresponding to C terminal amino acids 127-141 of Human C1D (NP_775269.1).

  • 阳性对照
    • Human skeletal muscle lysate.

性能

应用

Our Abpromise guarantee covers the use of ab80497 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
WB
  • 应用说明
    Peptide ELISA: antibody detection limit dilution 1/128000.
    WB: Use at a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 14 kDa (predicted molecular weight: 16 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能
      Plays a role in the recruitment of the RNA exosome complex to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA; this function may include MPHOSPH6. Can activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. Can induce apoptosis in a p53/TP53 dependent manner. May regulate the TRAX/TSN complex formation. Potentiates transcriptional repression by NR1D1 and THRB.
    • 组织特异性
      Ubiquitous. Expressed at very high levels in the hippocampus, medulla oblongata, mammary gland, thyroid and salivary gland. Expressed at high levels in the fetal; lung, liver and kidney. Expressed at low levels in skeletal muscle, appendix, heart, lung and colon.
    • 序列相似性
      Belongs to the C1D family.
    • 翻译后修饰
      Phosphorylated by PRKDC.
    • 细胞定位
      Cytoplasm. Nucleus > nucleolus. EXOSC10 is required for nucleolar localization.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 1110036E10Rik antibody
      • AI875855 antibody
      • C1D antibody
      • C1D DNA binding protein antibody
      • C1D_HUMAN antibody
      • hC1D antibody
      • LRP1 antibody
      • MGC12261 antibody
      • MGC14659 antibody
      • MGC188504 antibody
      • Nuclear DNA binding protein antibody
      • Nuclear nucleic acid binding protein C1D antibody
      • Nuclear nucleic acid-binding protein C1D antibody
      • rCG23324 antibody
      • RGD1560600 antibody
      • Small unique nuclear receptor corepressor antibody
      • SUNCOR antibody
      see all

    图片

    实验方案

    文献

    ab80497 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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