概述

  • 产品名称Anti-C14orf133抗体
  • 描述
    兔多克隆抗体to C14orf133
  • 经测试应用适用于: WB, IPmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • 免疫原

    Synthetic peptide, corresponding to a region between amino acids 443-493 of Human C14orf133 (NP_071350.2).

  • 阳性对照
    • HeLa, 293T, Jurkat and NIH3T3 whole cell lysates.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.09% Sodium azide
    Constituent: 99% Tris citrate/phosphate
    Note: pH 7 to 8
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab125084 was affinity purified using an epitope specific to C14orf133 immobilized on solid support.
  • 克隆多克隆
  • 同种型IgG

应用

Our Abpromise guarantee covers the use of ab125084 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/2000 - 1/10000. Predicted molecular weight: 57 kDa.
IP Use at 2-10 µg/mg of lysate.

靶标

  • 功能Plays a role in lysosomal trafficking. May play a role in epithelial polarization through stabilization of apical membrane protein content, possibly via the RAB11A-dependent apical recycling pathway. Also involved in direct or indirect transcriptional regulation of E-cadherin.
  • 疾病相关Defects in VIPAR are the cause of arthrogryposis-renal dysfunction-cholestasis syndrome type 2 (ARCS2) [MIM:613404]. ARCS2 is an autosomal recessive multisystem disorder, characterized by neurogenic arthrogryposis multiplex congenita, renal tubular dysfunction and neonatal cholestasis with bile duct hypoplasia and low gamma glutamyl transpeptidase activity. Platelet dysfunction is common. Note=In liver, CEACAM5 and ABCB11 are mislocalized and E-cadherin expression is decreased.
  • 序列相似性Belongs to the VIPAR family.
  • 细胞定位Early endosome. Recycling endosome. Late endosome.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Apical basolateral polarity regulator antibody
    • FLJ12707 antibody
    • hSPE-39 antibody
    • Protein spe-39 homolog antibody
    • SPE 39 antibody
    • SPE 39 protein antibody
    • SPE39 antibody
    • Uncharacterized protein C14orf133 antibody
    • vipar antibody
    • VIPAR_HUMAN antibody
    • VPS16B antibody
    • VPS33B interacting protein antibody
    • VPS33B interacting protein apical basolateral polarity regulator antibody
    • VPS33B interacting protein involved in polarity and apical protein restriction antibody
    • VPS33B-interacting protein antibody
    see all

Anti-C14orf133 antibody 图像

  • All lanes : Anti-C14orf133 antibody (ab125084) at 0.1 µg/ml

    Lane 1 : HeLa whole cell lysate at 50 µg
    Lane 2 : HeLa whole cell lysate at 15 µg
    Lane 3 : 293T whole cell lysate at 50 µg
    Lane 4 : Jurkat whole cell lysate at 50 µg
    Lane 5 : NIH3T3 whole cell lysate at 50 µg

    Developed using the ECL technique

    Predicted band size : 57 kDa


    Exposure time : 30 seconds
  • Detection of C14orf133 by Western Blot of Immunprecipitate.
    ab125084 at 1µg/ml staining C14orf133 in HeLa whole cell lysate immunoprecipitated using ab125084 at 6µg/mg lysate (1 mg/IP; 20% of IP loaded/lane).
    Detection: Chemiluminescence with exposure time of 30 seconds.

Anti-C14orf133 antibody (ab125084)参考文献

ab125084 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab125084.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"